Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected] (Q34043446)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected] (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1 reference

7

1 reference

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19 January 2020

Sylvia Samaniego

4

1 reference

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19 January 2020

Eleonora Olivotto

12

1 reference

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19 January 2020

Marco E. Bianchi

14

1 reference

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19 January 2020

author name string

Marianna Penzo

1

1 reference

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19 January 2020

Raffaella Molteni

2

1 reference

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19 January 2020

Tomomi Suda

3

1 reference

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19 January 2020

Angela Raucci

5

1 reference

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19 January 2020

David M Habiel

6

1 reference

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19 January 2020

Hui-Ping Jiang

8

1 reference

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19 January 2020

Jun Li

9

1 reference

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19 January 2020

Ruggero Pardi

10

1 reference

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19 January 2020

Roberta Palumbo

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Richard R Kew

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Kenneth B Marcu

15

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

15 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Journal of Immunology

1 reference

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19 January 2020

volume

184

1 reference

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19 January 2020

page(s)

4497-4509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2915896/fullTextXML

inferred from PubMed Central ID database lookup

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5 July 2018

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5 July 2018

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Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.

5 July 2018

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A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats

5 July 2018

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IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation

5 July 2018

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Shared principles in NF-kappaB signaling

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HMGB1 develops enhanced proinflammatory activity by binding to cytokines.

5 July 2018

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Src tyrosine kinases mediate activations of NF-kappaB and integrin signal during lipopolysaccharide-induced acute lung injury

5 July 2018

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Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation

5 July 2018

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Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

5 July 2018

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A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

5 July 2018

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Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity.

5 July 2018

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Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress

5 July 2018

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

5 July 2018

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A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

5 July 2018

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A fourth IkappaB protein within the NF-kappaB signaling module

5 July 2018

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Integrating cell-signalling pathways with NF-kappaB and IKK function

5 July 2018

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IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

5 July 2018

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The secretion of HMGB1 is required for the migration of maturing dendritic cells

5 July 2018

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Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin).

5 July 2018

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HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

5 July 2018

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The amphoterin (HMGB1)/receptor for advanced glycation end products (RAGE) pair modulates myoblast proliferation, apoptosis, adhesiveness, migration, and invasiveness. Functional inactivation of RAGE in L6 myoblasts results in tumor formation in viv

5 July 2018

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High mobility group box 1 protein interacts with multiple Toll-like receptors

5 July 2018

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NF-kappaB: linking inflammation and immunity to cancer development and progression

5 July 2018

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Understanding RAGE, the receptor for advanced glycation end products

5 July 2018

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5 July 2018

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Selective inhibition of the C5a chemotactic cofactor function of the vitamin D binding protein by 1,25(OH)2 vitamin D3.

5 July 2018

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Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival

5 July 2018

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p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

5 July 2018

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

5 July 2018

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Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes

5 July 2018

1 reference

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Essential role of IkappaB kinase alpha in the constitutive processing of NF-kappaB2 p100.

5 July 2018

1 reference

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RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

5 July 2018

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Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

5 July 2018

1 reference

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

5 July 2018

1 reference

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IkappaB kinases: key regulators of the NF-kappaB pathway

5 July 2018

1 reference

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IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

5 July 2018

1 reference

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Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

5 July 2018

1 reference

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Cell migration: integrating signals from front to back

5 July 2018

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Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

5 July 2018

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5 July 2018

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TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

5 July 2018

1 reference

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Rapid generation of inducible mouse mutants

5 July 2018

1 reference

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HMGB1 as a DNA-binding cytokine

5 July 2018

1 reference

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The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

5 July 2018

1 reference

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IKKalpha controls formation of the epidermis independently of NF-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

IKK1-deficient mice exhibit abnormal development of skin and skeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Limb and skin abnormalities in mice lacking IKKalpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Ligand-activated site-specific recombination in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Leukocyte locomotion and chemotaxis. New methods for evaluation, and demonstration of a cell-derived chemotactic factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

IkappaB kinase subunits alpha and gamma are required for activation of NF-kappaB and induction of apoptosis by mammalian reovirus

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Mouse bone marrow contains large numbers of functionally competent neutrophils

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2915896

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20231695

12 December 2020

inferred from PubMed ID database lookup

Thrombin-induced IL-6 production in human synovial fibroblasts is mediated by PAR1, phospholipase C, protein kinase C alpha, c-Src, NF-kappa B and p300 pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20231695

12 December 2020

inferred from PubMed ID database lookup

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20231695

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4049/JIMMUNOL.0903131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20231695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference