The effects of stem length and core placement on shRNA activity (Q33984111)

30 July 2017

The effects of stem length and core placement on shRNA activity (English)

1 reference

30 July 2017

Glen J McIntyre

1

1 reference

30 July 2017

Yi-Hsin Yu

series ordinal

2

1 reference

30 July 2017

Mehnaaz Lomas

series ordinal

3

1 reference

30 July 2017

Gregory C Fanning

series ordinal

4

1 reference

30 July 2017

8 August 2011

1 reference

30 July 2017

BMC Molecular Biology

1 reference

30 July 2017

12

1 reference

30 July 2017

34

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2199-12-34

30 July 2017

0 references

cites work

Asymmetrically designed siRNAs and shRNAs enhance the strand specificity and efficacy in RNAi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Potent RNAi by short RNA triggers.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Optimization of short hairpin RNA for lentiviral-mediated RNAi against WAS.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Defining the optimal parameters for hairpin-based knockdown constructs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Design and cloning strategies for constructing shRNA expression vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Second-generation shRNA libraries covering the mouse and human genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Functional polarity is introduced by Dicer processing of short substrate RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

MicroRNA biogenesis: coordinated cropping and dicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

The contributions of dsRNA structure to Dicer specificity and efficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Unlocking the potential of the human genome with RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Single processing center models for human Dicer and bacterial RNase III

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

MicroRNA precursors in motion: exportin-5 mediates their nuclear export

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Control of HIV-1 replication by RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Derivation and function of small interfering RNAs and microRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

A resource for large-scale RNA-interference-based screens in mammals.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Rational siRNA design for RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

MicroRNAs: genomics, biogenesis, mechanism, and function

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

5 July 2018

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Asymmetry in the assembly of the RNAi enzyme complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

The nuclear RNase III Drosha initiates microRNA processing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Promoter choice affects the potency of HIV-1 specific RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Mfold web server for nucleic acid folding and hybridization prediction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Killing the messenger: short RNAs that silence gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Simultaneous inhibition of GSK3alpha and GSK3beta using hairpin siRNA expression vectors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Ribonuclease activity and RNA binding of recombinant human Dicer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

MicroRNA maturation: stepwise processing and subcellular localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Gene silencing using micro-RNA designed hairpins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Effective expression of small interfering RNA in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

A system for stable expression of short interfering RNAs in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Stable suppression of gene expression by RNAi in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

RNA interference is mediated by 21- and 22-nucleotide RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Synthetic shRNAs as potent RNAi triggers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Cloning of short hairpin RNAs for gene knockdown in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

Use of RNA polymerase II to transcribe artificial microRNAs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Targeting cellular genes with PCR cassettes expressing short interfering RNAs.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175162

Induction of an interferon response by RNAi vectors in mammalian cells

29 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2199-12-34

21 January 2018

Identifiers

DOI

10.1186/1471-2199-12-34

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference