Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells (Q33977597)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547866%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells (English)

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5 February 2020

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corrigendum / erratum

Correction for Krieg et al., Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

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author

Carsten Krieg

series ordinal

1

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5 February 2020

Onur Boyman

series ordinal

4

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5 February 2020

3

Giuseppe Pantaleo

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5 February 2020

author name string

Sven Létourneau

series ordinal

2

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5 February 2020

language of work or name

English

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publication date

14 June 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547866%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

5 February 2020

published in

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5 February 2020

volume

107

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5 February 2020

issue

26

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5 February 2020

page(s)

11906-11911

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IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

5 February 2020

cites work

1 reference

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IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

28 July 2018

1 reference

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

28 July 2018

1 reference

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Suppression of murine allergic airway disease by IL-2:anti-IL-2 monoclonal antibody-induced regulatory T cells

28 July 2018

1 reference

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Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines

28 July 2018

1 reference

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An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

28 July 2018

1 reference

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Cytokines and T-cell homeostasis

28 July 2018

1 reference

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Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

28 July 2018

1 reference

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A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

28 July 2018

1 reference

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Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

28 July 2018

1 reference

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The role of nitric oxide in interleukin-2 therapy induced hypotension

28 July 2018

1 reference

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The IL-2 receptor complex: its structure, function, and target genes

28 July 2018

1 reference

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The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of P64/IL-2R gamma chain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

28 July 2018

1 reference

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Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

28 July 2018

1 reference

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Role of asialo-GM1-positive lymphoid cells in mediating the toxic effects of recombinant IL-2 in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

Passive immunization against tumor necrosis factor partially abrogates interleukin 2 toxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

Pentoxifylline inhibits interleukin-2-induced toxicity in C57BL/6 mice but preserves antitumor efficacy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

The biology of interleukin-2.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Application of IL-2 and other cytokines in renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Identification of a protein fragment of interleukin 2 responsible for vasopermeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Generation of low-toxicity interleukin-2 fusion proteins devoid of vasopermeability activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Unique structure of murine interleukin-2 as deduced from cloned cDNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Phase I trial of BAY 50-4798, an interleukin-2-specific agonist in advanced melanoma and renal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Memory-type CD8+ T cells protect IL-2 receptor alpha-deficient mice from systemic infection with herpes simplex virus type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

IL-2 receptor alpha(-/-) mice and the development of primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Allometric principles for interspecies extrapolation in toxicological risk assessment--empirical investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1002569107

Antigen-independent activation of memory cytotoxic T cells by interleukin 2

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900642

A T-cell-selective interleukin 2 mutein exhibits potent antitumor activity and is well tolerated in vivo

29 October 2018

1 reference

12 December 2020

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

1 reference

12 December 2020

Extravasation of intravascular fluid mediated by the systemic administration of recombinant interleukin 2

1 reference

12 December 2020

Interleukin-2 induced systemic toxicity: induction of mediators and immunopharmacologic intervention

1 reference

12 December 2020

Mechanisms of interleukin-2-induced hepatic toxicity

1 reference

12 December 2020

Human fibroblasts express functional IL-2 receptors formed by the IL-2R alpha- and beta-chain subunits: association of IL-2 binding with secretion of the monocyte chemoattractant protein-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1002569107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547866%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20547866%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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