Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions. (Q33917913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Novel inhibitors of InhA efficiently kill Mycobacterium tuberculosis under aerobic and anaerobic conditions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

2 February 2020

main subject

0 references

author

Anthony D. Baughn

2

1 reference

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2 February 2020

Lawrence W. Leung

4

1 reference

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2 February 2020

Christopher F Basler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

William Jacobs

10

1 reference

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2 February 2020

9

Joel S Freundlich

1 reference

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2 February 2020

author name string

Catherine Vilchèze

1

1 reference

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2 February 2020

JoAnn Tufariello

3

1 reference

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2 February 2020

Mack Kuo

5

1 reference

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2 February 2020

David Alland

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

James C Sacchettini

8

1 reference

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2 February 2020

language of work or name

English

0 references

publication date

31 May 2011

1 reference

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2 February 2020

number of pages

10

1 reference

Antimicrobial Agents and Chemotherapy

inferred from page(s)

published in

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2 February 2020

volume

55

1 reference

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2 February 2020

issue

8

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2 February 2020

page(s)

3889-3898

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New drugs and new regimens for the treatment of tuberculosis: review of the drug development pipeline and implications for national programmes

2 February 2020

cites work

1 reference

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A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis

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Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosis

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Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors

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5 July 2018

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5 July 2018

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5 July 2018

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Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

5 July 2018

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

5 July 2018

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Fatty acid biosynthesis as a target for novel antibacterials

5 July 2018

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The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance

5 July 2018

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Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

5 July 2018

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Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data

5 July 2018

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Mn(III) pyrophosphate as an efficient tool for studying the mode of action of isoniazid on the InhA protein of Mycobacterium tuberculosis

5 July 2018

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5 July 2018

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5 July 2018

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Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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29 October 2018

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Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs.

29 October 2018

1 reference

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Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.

29 October 2018

1 reference

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High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains ofMycobacterium tuberculosis

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21628538

12 December 2020

inferred from PubMed ID database lookup

Action mechanism of antitubercular isoniazid. Activation by Mycobacterium tuberculosis KatG, isolation, and characterization of inha inhibitor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21628538

12 December 2020

inferred from PubMed ID database lookup

Spontaneous Formation of the Bioactive Form of the Tuberculosis Drug Isoniazid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21628538

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.00266-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21628538%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

21628538

1 reference