Chemically induced dimerization of dihydrofolate reductase by a homobifunctional dimer of methotrexate. (Q33901080)

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6 November 2019

title

Chemically induced dimerization of dihydrofolate reductase by a homobifunctional dimer of methotrexate (English)

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6 November 2019

2

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6 November 2019

author name string

S J Kopytek

series ordinal

1

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6 November 2019

J C Dyer

series ordinal

3

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6 November 2019

J C Hu

series ordinal

4

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6 November 2019

publication date

1 May 2000

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6 November 2019

published in

Chemistry and Biology

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6 November 2019

volume

7

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6 November 2019

issue

5

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6 November 2019

page(s)

313-321

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A versatile synthetic dimerizer for the regulation of protein-protein interactions

6 November 2019

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Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain

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Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugates.

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Identifiers

DOI

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6 November 2019

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