A humanized system for pharmacologic control of gene expression (Q34394730)

1 August 2017

title

A humanized system for pharmacologic control of gene expression (English)

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1 August 2017

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Rivera VM

1

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1 August 2017

Clackson T

2

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Natesan S

3

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Pollock R

4

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Amara JF

5

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Keenan T

6

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Magari SR

7

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Phillips T

8

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Courage NL

9

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Cerasoli F Jr

10

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Holt DA

11

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Gilman M

12

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publication date

1 September 1996

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1 August 2017

language of work or name

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1 August 2017

volume

2

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1 August 2017

issue

9

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1 August 2017

page(s)

1028-1032

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Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

1 August 2017

cites work

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Creating conditional mutations in mammals

21 January 2018

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How eukaryotic transcriptional activators work

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

A novel genetic system to detect protein-protein interactions

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Proximity versus allostery: the role of regulated protein dimerization in biology

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Molecular cloning and overexpression of the human FK506-binding protein FKBP

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Human growth hormone as a reporter gene in regulation studies employing transient gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

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https://api.crossref.org/works/10.1038%2FNM0996-1028

Controlling Signal Transduction with Synthetic Ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

A general strategy for producing conditional alleles of Src-like tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Signal transduction in T lymphocytes using a conditional allele of Sos

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https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

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https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Preclinical evaluation of a new potent immunosuppressive agent, rapamycin

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https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Rapamycin, a potent immunosuppressive drug for vascularized heart, kidney, and small bowel transplantation in the rat.

1 reference

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7 January 2021

Structure-based design of transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Long-term production and delivery of human growth hormone in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Antigenic peptide binding by class I and class II histocompatibility proteins

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

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https://api.crossref.org/works/10.1038%2FNM0996-1028

7 January 2021

Identifiers

DOI

10.1038/NM0996-1028

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1 August 2017

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