Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response (Q33886159)

29 July 2017

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response (English)

1 reference

respiratory syncytial virus

29 July 2017

0 references

RSV NS1 protein

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modulation by virus of host process

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3

Cyril Le Nouën

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author name string

Shirin Munir

1

1 reference

29 July 2017

Philippa Hillyer

2

1 reference

29 July 2017

Cyril Le Nouën

3

1 reference

29 July 2017

Ursula J Buchholz

4

1 reference

29 July 2017

Ronald L Rabin

5

1 reference

29 July 2017

Peter L Collins

6

1 reference

29 July 2017

Alexander Bukreyev

7

1 reference

29 July 2017

21 April 2011

1 reference

29 July 2017

1 reference

29 July 2017

7

1 reference

29 July 2017

e1001336

1 reference

29 July 2017

4

1 reference

Creative Commons CC0 License

29 July 2017

start time

21 April 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Human respiratory syncytial virus nonstructural protein NS2 antagonizes the activation of beta interferon transcription by interacting with RIG-I

28 July 2018

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The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes

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Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells

28 July 2018

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IL-23 enhances host defense against vaccinia virus infection via a mechanism partly involving IL-17.

28 July 2018

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28 July 2018

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28 July 2018

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Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase

28 July 2018

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Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

28 July 2018

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Differential receptor subunit affinities of type I interferons govern differential signal activation.

28 July 2018

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Stimulated plasmacytoid dendritic cells impair human T-cell development

28 July 2018

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Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10.

28 July 2018

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Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virus

28 July 2018

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Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung.

28 July 2018

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Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

28 July 2018

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Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus

28 July 2018

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Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness

28 July 2018

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Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation

28 July 2018

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Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]

28 July 2018

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Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells

28 July 2018

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Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3

28 July 2018

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28 July 2018

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Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthood

28 July 2018

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A common haplotype of interleukin-4 gene IL4 is associated with severe respiratory syncytial virus disease in Korean children

28 July 2018

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28 July 2018

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Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

28 July 2018

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28 July 2018

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Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infection

28 July 2018

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Induction of bystander T cell proliferation by viruses and type I interferon in vivo

28 July 2018

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Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alpha E beta 7 integrin

28 July 2018

1 reference

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Immunity to and frequency of reinfection with respiratory syncytial virus

28 July 2018

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Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking

28 July 2018

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Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice

28 July 2018

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Respiratory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children

28 July 2018

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Modification of tumor cells by a low dose of Newcastle disease virus. III. Potentiation of tumor-specific cytolytic T cell activity via induction of interferon-alpha/beta

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Type I interferon (IFN alpha) acts directly on human memory CD4+ T cells altering their response to antigen.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Viral and host factors in human respiratory syncytial virus pathogenesis

21 January 2018

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Effects of nonstructural proteins NS1 and NS2 of human respiratory syncytial virus on interferon regulatory factor 3, NF-kappaB, and proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growth

21 January 2018

1 reference

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Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2.

21 January 2018

1 reference

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A role for TNF in limiting the duration of CTL effector phase and magnitude of CD8 T cell memory.

21 January 2018

1 reference

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Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

CD4+ T cell plasticity-Th2 cells join the crowd.

21 January 2018

1 reference

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Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

21 January 2018

1 reference

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Cellular response to respiratory viruses with particular reference to children with disorders of cell-mediated immunity

21 January 2018

1 reference

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E 7 (CD103) Expression Identifies a Highly Active, Tonsil-Resident Effector-Memory CTL Population

21 January 2018

1 reference

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Role of the mucosal integrin alpha(E)(CD103)beta(7) in tissue-restricted cytotoxicity.

21 January 2018

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Interleukin-17 family members and inflammation

21 January 2018

1 reference

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Human genetic factors and respiratory syncytial virus disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Association of severe respiratory syncytial virus bronchiolitis with interleukin-4 and interleukin-4 receptor alpha polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

IL-13 genetic polymorphism identifies children with late wheezing after respiratory syncytial virus infection

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Genetic association study for RSV bronchiolitis in infancy at the 5q31 cytokine cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001336

Type I Interferon Induction Pathway, but Not Released Interferon, Participates in the Maturation of Dendritic Cells Induced by Negative‐Strand RNA Viruses

21 January 2018

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The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines

21 January 2018

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Induction and effector functions of T(H)17 cells.

21 January 2018

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Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production

21 January 2018

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CD8+ T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection

21 January 2018

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Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization

21 January 2018

1 reference

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Effects of human respiratory syncytial virus, metapneumovirus, parainfluenza virus 3 and influenza virus on CD4+ T cell activation by dendritic cells

21 January 2018

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A novel role for neutrophils as critical activators of NK cells

21 January 2018

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Respiratory syncytial virus (RSV) evades the human adaptive immune system by skewing the Th1/Th2 cytokine balance toward increased levels of Th2 cytokines and IgE, markers of allergy--a review

29 October 2018

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The role of Stat4 in species-specific regulation of Th cell development by type I IFNs.

29 October 2018

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Role of TNF-alpha in CD8+ cytotoxic T lymphocyte-mediated lysis.

29 October 2018

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Type I interferons (IFN-alpha and -beta) suppress cytotoxin (tumor necrosis factor-alpha and lymphotoxin) production by mitogen-stimulated human peripheral blood mononuclear cell

29 October 2018

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Interleukin-17A modulates human airway epithelial responses to human rhinovirus infection

29 October 2018

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12 December 2020

Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking

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12 December 2020

IL-4 and IFN (alpha and gamma) exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human T cell clones

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12 December 2020

Involvement of alpha-interferon in HIV-1 induced immunosuppression. A potential target for AIDS prophylaxis and treatment

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12 December 2020

Differential expression of alpha E beta 7 integrins on bronchoalveolar lavage T lymphocyte subsets: regulation by alpha 4 beta 1-integrin crosslinking and TGF-beta

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12 December 2020

Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development

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12 December 2020

Type I interferons inhibit maturation and activation of mouse Langerhans cells

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12 December 2020

Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-gamma, IL-4 and IL-10

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12 December 2020

Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes

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12 December 2020

IFN-alpha2a induces IP-10/CXCL10 and MIG/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

A new murine CD4+ T cell subset with an unrestricted cytokine profile

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12 December 2020

10.1371/JOURNAL.PPAT.1001336

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference