Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2. (Q42515803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17627610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2 (English)

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2 January 2020

4

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2 January 2020

Sandra Pellegrini

5

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2 January 2020

author name string

Zrinka Marijanovic

1

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2 January 2020

Josiane Ragimbeau

2

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2 January 2020

José van der Heyden

3

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2 January 2020

language of work or name

English

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publication date

1 October 2007

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2 January 2020

number of pages

11

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inferred from page(s)

published in

Biochemical Journal

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2 January 2020

volume

407

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2 January 2020

page(s)

141-151

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2 January 2020

issue

1

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Complex modulation of cell type-specific signaling in response to type I interferons

2 January 2020

cites work

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28 May 2018

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Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors

28 May 2018

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TYK2 activity promotes ligand-induced IFNAR1 proteolysis

28 May 2018

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Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta

28 May 2018

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28 May 2018

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Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor

28 May 2018

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28 May 2018

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Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C

28 May 2018

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28 May 2018

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SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor

28 May 2018

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

28 May 2018

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The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

28 May 2018

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The Janus kinase family of protein tyrosine kinases and their role in signaling

28 May 2018

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Formation of a uniquely stable type I interferon receptor complex by interferon beta is dependent upon particular interactions between interferon beta and its receptor and independent of tyrosine phosphorylation

28 May 2018

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

28 May 2018

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28 May 2018

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Alternative intracellular routing of ErbB receptors may determine signaling potency

28 May 2018

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The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation

28 May 2018

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Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

28 May 2018

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The human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoprotein

28 May 2018

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Differences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptor

28 May 2018

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Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

28 May 2018

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Differential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN-alpha and IFN-beta

28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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28 May 2018

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Mutational analysis of the IFNAR1 binding site on IFNalpha2 reveals the architecture of a weak ligand-receptor binding-site.

16 August 2018

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16 August 2018

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16 August 2018

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Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction

16 August 2018

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12 December 2020

Contributions of cloned type I interferon receptor subunits to differential ligand binding1

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12 December 2020

Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis

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12 December 2020

Activation of the Jak-Stat Pathway in Cells That Exhibit Selective Sensitivity to the Antiviral Effects of IFN-beta Compared with IFN-alpha

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12 December 2020

Both proteasomes and lysosomes degrade the activated erythropoietin receptor

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12 December 2020

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

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12 December 2020

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

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12 December 2020

Comparison of gene expression patterns induced by treatment of human umbilical vein endothelial cells with IFN-alpha 2b vs. IFN-beta 1a: understanding the functional relationship between distinct type I interferons that act through a common receptor

1 reference

12 December 2020

Mechanisms for regulation of cellular responsiveness to human IFN-beta1a

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12 December 2020

Identifiers

DOI

10.1042/BJ20070605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17627610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17627610%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference