Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation (Q33873603)

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English	Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation (English)

1 reference

Europe PubMed Central

29 July 2017

Jo Lynne Harenza

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Jo Lynne Harenza

4

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Todd K O'Buckley

object named as

Todd K O'Buckley

2

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Robert W. Williams

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Robert W Williams

7

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object named as

Patrizia Porcu

1

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author name string

Soomin C Song

3

1 reference

Europe PubMed Central

29 July 2017

Lu Lu

5

1 reference

Europe PubMed Central

29 July 2017

Xusheng Wang

6

1 reference

Europe PubMed Central

29 July 2017

Michael F Miles

8

1 reference

Europe PubMed Central

29 July 2017

A Leslie Morrow

9

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

8 April 2011

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

6

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Europe PubMed Central

29 July 2017

4

1 reference

Europe PubMed Central

29 July 2017

e18405

1 reference

Europe PubMed Central

29 July 2017

Individual differences in prefrontal cortex function and the transition from drug use to drug dependence

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Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans

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Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis

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High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains.

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5 July 2018

The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008.

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5 July 2018

Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain

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An overview of genetic influences in alcoholism.

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Review. Neurogenetic studies of alcohol addiction

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The stressed prefrontal cortex. Left? Right!

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5 July 2018

Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects

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Progesterone exerts neuroprotective effects after brain injury

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Progesterone: therapeutic opportunities for neuroprotection and myelin repair.

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Mechanisms of neurosteroid interactions with GABA(A) receptors.

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Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior

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A high-resolution single nucleotide polymorphism genetic map of the mouse genome

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Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus

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Neuroactive steroids as modulators of depression and anxiety

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Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis

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A new set of BXD recombinant inbred lines from advanced intercross populations in mice

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WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior

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WebQTL: web-based complex trait analysis

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Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive

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Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

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Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice

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5 July 2018

Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.

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5 July 2018

Shared genes influence sensitivity to the effects of ethanol on locomotor and anxiety-like behaviors, and the stress axis

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The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis

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Identifying genes for alcohol and drug sensitivity: recent progress and future directions

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Brain neurosteroids during the mouse oestrous cycle.

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Permutation tests for multiple loci affecting a quantitative character

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An 8-year follow-up of 450 sons of alcoholic and control subjects

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5 July 2018

Low level of response to alcohol as a predictor of future alcoholism

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Genetic animal models of alcohol and drug abuse

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5 July 2018

Alcohol acceptance, preference, and sensitivity in mice. II. Quantitative trait loci mapping analysis using BXD recombinant inbred strains.

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Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

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Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF)

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Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

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Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology

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5 July 2018

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

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5 July 2018

Systemic ethanol administration elevates deoxycorticosterone levels and chronic ethanol exposure attenuates this response

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Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats.

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21 January 2018

Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats

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Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats

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Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals

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Alcohol acceptance, preference, and sensitivity in mice. I. Quantitative genetic analysis using BXD recombinant inbred strains.

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21 January 2018

Effect of within-strain sample size on QTL detection and mapping using recombinant inbred mouse strains

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Neurosteroids: endogenous allosteric modulators of GABA(A) receptors.

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Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of ethanol action?

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Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task

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Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats

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Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one

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GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride

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Autosomal linkage analysis for the level of response to alcohol

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The search for genes related to a low-level response to alcohol determined by alcohol challenges

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Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder

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HPA axis dysregulation in mice overexpressing corticotropin releasing hormone

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Steroid metabolism by constitutive cytochromes P450.

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Genetics of alcohol dependence

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An evaluation of the level of response to alcohol, externalizing symptoms, and depressive symptoms as predictors of alcoholism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072994

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Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

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29 October 2018

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of alcoholism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of genes affecting alcohol drinking in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21494628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0018405

1 reference

Europe PubMed Central

29 July 2017

2011PLoSO...618405P

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1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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