Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats (Q44516022)

3 December 2017

Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats (English)

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3 December 2017

Rahul T Khisti

1

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3 December 2017

Margaret J VanDoren

series ordinal

2

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3 December 2017

Todd O'Buckley

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3

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3 December 2017

A Leslie Morrow

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4

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3 December 2017

language of work or name

English

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publication date

1 August 2003

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3 December 2017

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3 December 2017

980

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3 December 2017

255-265

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3 December 2017

2

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Redox effects of ethanol on steroid metabolism

3 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Purification of the NADPH:5 alpha-dihydroprogesterone 3 alpha-hydroxysteroid oxidoreductase from female rat pituitary cytosol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Long-term ethanol and nicotine treatment elicit tolerance to ethanol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Initial sensitivity and tolerance to ethanol in mice: correlations among open field activity, hypothermia, and loss of righting reflex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Tolerance to the anticonvulsant activity of midazolam and allopregnanolone in a model of picrotoxin seizures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The influence of subchronic administration of the neurosteroid allopregnanolone on sleep in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Hypothalamic 5 alpha-reductase and 3 alpha-oxidoreductase activity in the male rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Evidence that 3α-hydroxy-5α-pregnan-20-one is a physiologically relevant modulator of gaba-ergic neurotransmission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The reinforcing effects of ethanol are altered by the endogenous neurosteroid, allopregnanolone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

GABAergic neurosteroid modulation of ethanol actions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Allopregnanolone (THP) mediates anesthetic effects of progesterone in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Regional and interspecies differences in brain progesterone metabolism

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

During anesthetic-induced activation of hypothalamic pituitary adrenal axis, blood-borne steroids fail to contribute to the anesthetic effect

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Inhibition of brain 5 alpha-reductase in pregnant rats: effects on enzymatic and behavioral activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Effects of the acute administration of ethanol on the sleep of the rat: A dose-response study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

3 alpha-hydroxy-5 alpha-pregnan-20-one is the only active anesthetic steroid in anesthetized mouse brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Effects of central and systemic injections of peripheral benzodiazepine receptor ligands on the anxiolytic actions of ethanol in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of ethanol action?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Inhibition of human steroid 5alpha reductases type I and II by 6-aza-steroids: structural determinants of one-step vs two-step mechanism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The effects of the neuroactive steroid 3 alpha,5 alpha-THDOC on sleep in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Alcohol stimulates ACTH secretion in the rat: mechanisms of action and interactions with other stimuli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Dehydroepiandrosterone (DHEA) is a neuroactive neurosteroid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Ethanol as a hypnotic in insomniacs: self administration and effects on sleep and mood

7 January 2021

1 reference

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Effects of fluoxetine, indomethacine and placebo on 3 alpha, 5 alpha tetrahydroprogesterone (THP) plasma levels in uncomplicated alcohol withdrawal.

7 January 2021

1 reference

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Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5alpha-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Glucocorticoids antagonize the sedative action of ethanol in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Identification of a unique Sertoli cell steroid as 3-alpha-hydroxy-4-pregnen-20-one (3 alpha-dihydroprogesterone: 3 alpha-DHP)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

Effects of chronic and acute ethanol administration on sleep in laboratory rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902978-0

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-8993(03)02978-0

1 reference

3 December 2017

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