Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation. (Q33839818)

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18 January 2020

title

Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation (English)

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18 January 2020

7

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18 January 2020

author name string

Hui Yu

1

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18 January 2020

Hongmei Shen

2

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18 January 2020

Youzhong Yuan

3

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18 January 2020

Richard XuFeng

4

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18 January 2020

Xiaoxia Hu

5

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18 January 2020

Sean P Garrison

6

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18 January 2020

Jian Yu

8

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18 January 2020

Gerard P Zambetti

9

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18 January 2020

Tao Cheng

10

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18 January 2020

language of work or name

English

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publication date

22 February 2010

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18 January 2020

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18 January 2020

volume

115

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18 January 2020

issue

17

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18 January 2020

page(s)

3472-3480

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Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis

18 January 2020

cites work

1 reference

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PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome

5 July 2018

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Flow cytometry-based cell cycle measurement of mouse hematopoietic stem and progenitor cells

5 July 2018

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Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

5 July 2018

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The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

5 July 2018

1 reference

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Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

5 July 2018

1 reference

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Hematopoietic stem cell exhaustion impacted by p18 INK4C and p21 Cip1/Waf1 in opposite manners

5 July 2018

1 reference

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Total body irradiation selectively induces murine hematopoietic stem cell senescence

5 July 2018

1 reference

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BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.

5 July 2018

1 reference

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

5 July 2018

1 reference

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The transcriptional targets of p53 in apoptosis control

5 July 2018

1 reference

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

5 July 2018

1 reference

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Bone marrow origin of myofibroblasts in irradiation pulmonary fibrosis

5 July 2018

1 reference

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Live or let die: the cell's response to p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

PUMA, a novel proapoptotic gene, is induced by p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

PUMA induces the rapid apoptosis of colorectal cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

5 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

In vitro self-renewal division of hematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867261

Cell cycle. Piecing together the p53 puzzle.

5 July 2018

1 reference

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

5 July 2018

1 reference

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The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

5 July 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

5 July 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

5 July 2018

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow

5 July 2018

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Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy

5 July 2018

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Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure

5 July 2018

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Effects of transplantation on the primitive immunohematopoietic stem cell

5 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

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Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

5 July 2018

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A Limited role for p21Cip1/Waf1 in maintaining normal hematopoietic stem cell functioning.

29 October 2018

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Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice.

29 October 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

29 October 2018

1 reference

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p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

29 October 2018

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12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

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12 December 2020

The p53-deficient hemopoietic stem cells: their resistance to radiation-apoptosis, but lasted transiently

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12 December 2020

atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity

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12 December 2020

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

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12 December 2020

p53 and p21 regulate error-prone DNA repair to yield a lower mutation load

1 reference

12 December 2020

10.1182/BLOOD-2009-10-248278

Identifiers

DOI

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18 January 2020

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18 January 2020

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