Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade (Q33835454)

29 July 2017

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade (English)

1 reference

29 July 2017

12

1 reference

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3 June 2020

Jason M Schenkel

15

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3 June 2020

Shelley L. Berger

18

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3 June 2020

17

W Nicholas Haining

1 reference

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3 June 2020

author name string

Kristen E Pauken

1

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3 June 2020

Morgan A Sammons

2

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3 June 2020

Pamela M Odorizzi

3

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3 June 2020

Sasikanth Manne

4

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3 June 2020

Jernej Godec

5

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3 June 2020

Omar Khan

6

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3 June 2020

Adam M Drake

7

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3 June 2020

Zeyu Chen

8

1 reference

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3 June 2020

Debattama R Sen

9

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3 June 2020

Makoto Kurachi

10

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3 June 2020

R Anthony Barnitz

11

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3 June 2020

Bertram Bengsch

13

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3 June 2020

Alexander C Huang

14

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3 June 2020

Golnaz Vahedi

16

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3 June 2020

E John Wherry

19

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3 June 2020

language of work or name

English

0 references

publication date

27 October 2016

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27789795%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

354

1 reference

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3 June 2020

issue

6316

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3 June 2020

page(s)

1160-1165

1 reference

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T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections

3 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Molecular and cellular insights into T cell exhaustion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

The future of immune checkpoint therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

The role of chromatin dynamics in immune cell development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Epigenetic manipulation restores functions of defective CD8⁺ T cells from chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Selective effects of PD-1 on Akt and Ras pathways regulate molecular components of the cell cycle and inhibit T cell proliferation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

NFATc1 regulates PD-1 expression upon T cell activation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Restoring function in exhausted CD8 T cells during chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5484795

Immune modulation in cancer with antibodies

28 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Wellington-bootstrap: differential DNase-seq footprinting identifies cell-type determining transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAF2807

IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27789795

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAF2807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27789795%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27789795%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference