Educating T cells: early events in the differentiation and commitment of cytokine-producing CD4+ and CD8+ T cells (Q33833190)

29 July 2017

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title

Educating T cells: early events in the differentiation and commitment of cytokine-producing CD4+ and CD8+ T cells (English)

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29 July 2017

Kelso A

1

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29 July 2017

1 January 1999

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Seminars in Immunopathology

29 July 2017

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29 July 2017

21

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29 July 2017

3

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29 July 2017

231-248

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https://scigraph.springernature.com/pub.10.1007/s002810050065

29 July 2017

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cites work

Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

1 reference

12 December 2020

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

12 December 2020

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

1 reference

12 December 2020

T lymphocyte differentiation in the periphery

1 reference

12 December 2020

A single peripheral CD8+ T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions

1 reference

12 December 2020

Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development

1 reference

12 December 2020

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

12 December 2020

In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines.

1 reference

12 December 2020

Monoallelic expression of the interleukin-2 locus

1 reference

12 December 2020

Heterogeneity of single cell cytokine gene expression in clonal T cell populations

1 reference

12 December 2020

Genetic regulation of commitment to interleukin 4 production by a CD4(+) T cell-intrinsic mechanism

1 reference

12 December 2020

Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype

1 reference

12 December 2020

CD28 costimulation promotes the production of Th2 cytokines

1 reference

12 December 2020

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones

1 reference

12 December 2020

Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles

1 reference

12 December 2020

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

12 December 2020

Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells.

1 reference

12 December 2020

Regulation of expression of the human interferon gamma gene

1 reference

12 December 2020

Characterisation of inducible DNase I hypersensitive sites flanking the human interleukin-5 gene

1 reference

12 December 2020

Regulation of T helper cell differentiation by STAT molecules

1 reference

12 December 2020

Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype.

1 reference

12 December 2020

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

1 reference

12 December 2020

Transcription of individual genes in eukaryotic cells occurs randomly and infrequently

1 reference

12 December 2020

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

1 reference

12 December 2020

Th1 and Th2 subsets: paradigms lost?

1 reference

12 December 2020

T cell antigen receptor signal transduction pathways

1 reference

12 December 2020

Differential activation of T cell cytokine production by the extracellular signal-regulated kinase (ERK) signaling pathway

1 reference

12 December 2020

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

1 reference

12 December 2020

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.

1 reference

12 December 2020

Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level

1 reference

12 December 2020

The expanding universe of T-cell subsets: Th1, Th2 and more.

1 reference

12 December 2020

IL-4 directs the development of Th2-like helper effectors

1 reference

12 December 2020

A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

1 reference

12 December 2020

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

1 reference

12 December 2020

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

1 reference

12 December 2020

Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells.

1 reference

12 December 2020

Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry

1 reference

12 December 2020

Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production

1 reference

12 December 2020

Cutting edge: stable epigenetic inheritance of regional IFN-gamma promoter demethylation in CD44highCD8+ T lymphocytes.

1 reference

12 December 2020

In differentiated CD4+ T cells, interleukin 4 production is cytokine-autonomous, whereas interferon gamma production is cytokine-dependent

1 reference

12 December 2020

Effect of interleukin-10 on dendritic cell maturation and function

1 reference

12 December 2020

Lineage-specific requirement for signal transducer and activator of transcription (Stat)4 in interferon gamma production from CD4(+) versus CD8(+) T cells

1 reference

12 December 2020

Heterogeneity in lymphokine profiles of CD4+ and CD8+ T cells and clones activated in vivo and in vitro

1 reference

12 December 2020

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

1 reference

12 December 2020

Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like responsein vivo

1 reference

12 December 2020

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

12 December 2020

Independent regulation of cytokine genes in T cells: the paradox in the paradigm.

1 reference

12 December 2020

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

1 reference

12 December 2020

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

1 reference

12 December 2020

Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4.

1 reference

12 December 2020

Functional diversity of helper T lymphocytes

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12 December 2020

Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones

1 reference

12 December 2020

Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells.

1 reference

12 December 2020

Tpm1, a locus controlling IL-12 responsiveness, acts by a cell-autonomous mechanism

1 reference

12 December 2020

Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses

1 reference

12 December 2020

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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12 December 2020

CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo

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12 December 2020

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

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12 December 2020

Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

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12 December 2020

Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells

1 reference

12 December 2020

CD8+ T cells can be primed in vitro to produce IL-4

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12 December 2020

Helper T cell differentiation is controlled by the cell cycle

1 reference

12 December 2020

GM-CSF Expression is Preferential to Multi-CSF (IL-3) Expression in Murine T Lymphocyte Clones

1 reference

12 December 2020

Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death

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12 December 2020

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

1 reference

12 December 2020

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1 reference

12 December 2020

IL-4 and prostaglandin E2 inhibit hypomethylation of the 5' regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells

1 reference

12 December 2020

Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions

1 reference

12 December 2020

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

1 reference

12 December 2020

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

12 December 2020

The production of two Th2 cytokines, interleukin-4 and interleukin-10, is controlled independently by locus Cypr1 and by loci Cypr2 and Cypr3 , respectively

1 reference

12 December 2020

Transcription factors in lymphocyte development--T and B cells get together

1 reference

12 December 2020

Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines.

1 reference

12 December 2020

Profiles of lymphokine activities and helper function for IgE in human T cell clones

1 reference

12 December 2020

Single-cell analysis by RT-PCR reveals differential expression of multiple type 1 and 2 cytokine genes among cells within polarized CD4+ T cell populations

1 reference

12 December 2020

Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells.

1 reference

12 December 2020

Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene

1 reference

12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

12 December 2020

Activation of the extracellular signal-regulated kinase pathway is differentially required for TCR-stimulated production of six cytokines in primary T lymphocytes

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12 December 2020

Distinct dendritic cell subsets differentially regulate the class of immune response in vivo

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12 December 2020

Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells

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12 December 2020

Determination of cytokine co-expression in individual splenic CD4+ and CD8+ T cells from influenza virus-immune mice

1 reference

12 December 2020

Enumeration of lymphokine mRNA-containing cells in vivo in a murine graft-versus-host reaction using the PCR.

1 reference

12 December 2020

The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells

1 reference

12 December 2020

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

1 reference

12 December 2020

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

1 reference

12 December 2020

Analysis of cytokine patterns produced by individual CD4+ lymph node cells during experimental murine leishmaniasis in resistant and susceptible mice

1 reference

12 December 2020

Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes.

1 reference

12 December 2020

Stability of Th1 and Th2 populations

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12 December 2020

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

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12 December 2020

The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.

1 reference

12 December 2020

Critical role of NK1+ T cells in IL-12-induced immune responses in vivo

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12 December 2020

From TCR Engagement to T Cell Activation

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12 December 2020

A common precursor for CD4+ T cells producing IL-2 or IL-4

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12 December 2020

Signals and signs for lymphocyte responses

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12 December 2020

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

12 December 2020

Association of the interferon-gamma receptor variant (Val14Met) with systemic lupus erythematosus

1 reference

12 December 2020

Impaired interleukin 4 signaling in T helper type 1 cells.

1 reference

12 December 2020

Changes in the precursor frequencies of IL-4 and IFN-gamma secreting CD4+ cells correlate with resolution of lesions in murine cutaneous leishmaniasis

1 reference

12 December 2020

Oligonucleotide adjuvants for T helper 1 (Th1)-specific vaccination

1 reference

12 December 2020

The mechanism of in vitro T helper cell type 1 to T helper cell type 2 switching in highly polarized Leishmania major-specific T cell populations

1 reference

12 December 2020

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells

1 reference

12 December 2020

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation

1 reference

12 December 2020

Cytokine transcriptional events during helper T cell subset differentiation

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12 December 2020

Regulation of IL-4 expression by activation of individual alleles

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12 December 2020

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

1 reference

12 December 2020

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells

1 reference

12 December 2020

IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

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12 December 2020

Reciprocal control of T helper cell and dendritic cell differentiation

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12 December 2020

Mouse CD1-specific NK1 T cells: development, specificity, and function

1 reference

12 December 2020

Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1

1 reference

12 December 2020

Oral tolerance: immune mechanisms and treatment of autoimmune diseases

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12 December 2020

Acquisition of lymphokine-producing phenotype by CD4+ T cells

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12 December 2020

Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

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12 December 2020

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

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12 December 2020

High sensitivity mapping of methylated cytosines

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12 December 2020

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

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12 December 2020

Control of messenger RNA stability

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12 December 2020

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

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12 December 2020

Mice with a fluorescent marker for interleukin 2 gene activation

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12 December 2020

A new murine CD4+ T cell subset with an unrestricted cytokine profile

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12 December 2020

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

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12 December 2020

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

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12 December 2020

Genetics of allergy and asthma

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12 December 2020

Production of two hemopoietic growth factors is differentially regulated in single T lymphocytes activated with an anti-T cell receptor antibody

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12 December 2020

Identifiers

DOI

10.1007/S002810050065

1 reference

PubMed ID

10666771

Dimensions Publication ID

29 July 2017

1054514367

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Fatcat ID

release_5fyw2jnytvbs3btyvihhib2goy

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Fatcat

https://api.fatcat.wiki/v0/release/5fyw2jnytvbs3btyvihhib2goy

24 November 2022

mapped directly with Wikidata item

PubMed ID

10666771

1 reference

PubMed ID

10666771