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Single Cell Analysis Reveals Regulated Hierarchical T Cell Antigen Receptor Signaling Thresholds and Intraclonal Heterogeneity for Individual Cytokine Responses of CD4+ T Cells (Q28755947)

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scientific article (publication date: 29 August 1997)

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English	Single Cell Analysis Reveals Regulated Hierarchical T Cell Antigen Receptor Signaling Thresholds and Intraclonal Heterogeneity for Individual Cytokine Responses of CD4+ T Cells	scientific article (publication date: 29 August 1997)

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scholarly article

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Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells (English)

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Single Cell Analysis Reveals Regulated Hierarchical T Cell Antigen Receptor Signaling Thresholds and Intraclonal Heterogeneity for Individual Cytokine Responses of CD4+ T Cells (English)

1 reference

10.1084/JEM.186.5.757

https://api.crossref.org/works/10.1084/JEM.186.5.757

13 November 2024

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signal transduction

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

1

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Y. Itoh

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

author name string

R. N. Germain

2

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

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29 August 1997

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https://rupress.org/jem/article-pdf/186/5/757/1113368/97-0874.pdf

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

https://europepmc.org/articles/PMC2199012

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

https://europepmc.org/articles/PMC2199012?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9271591

13 November 2024

https://rupress.org/jem/article-pdf/186/5/757/1684325/97-0874.pdf

1 reference

10.1084/JEM.186.5.757

https://api.crossref.org/works/10.1084/JEM.186.5.757

13 November 2024

Journal of Experimental Medicine

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186

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5

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757-66

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The role of the CD28 receptor during T cell responses to antigen

2 references

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16 March 2017

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T cell receptor antagonist peptides induce positive selection

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Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists

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Models of T cell anergy: is there a common molecular mechanism?

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T cell activation determined by T cell receptor number and tunable thresholds.

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3 June 2018

Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling

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3 June 2018

Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution

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3 June 2018

Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors.

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3 June 2018

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1 reference

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3 June 2018

Specificity and flexibility in thymic selection

1 reference

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3 June 2018

Acquisition of lymphokine-producing phenotype by CD4+ T cells

1 reference

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3 June 2018

Signals and signs for lymphocyte responses

1 reference

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3 June 2018

Lymphocyte responses and cytokines

1 reference

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3 June 2018

Class II transactivator regulates the expression of multiple genes involved in antigen presentation

1 reference

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3 June 2018

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

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3 June 2018

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

1 reference

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Co-stimulation lowers the threshold for activation of naive T cells by bacterial superantigens.

1 reference

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3 June 2018

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

1 reference

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3 June 2018

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

1 reference

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3 June 2018

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

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Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene

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10.1084/JEM.186.5.757

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