Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity (Q33824203)

29 July 2017

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity (English)

1 reference

29 July 2017

Yoshimi Naruo

1

1 reference

29 July 2017

Takeshi Nagashima

2

1 reference

29 July 2017

Ryoko Ushikoshi-Nakayama

3

1 reference

29 July 2017

Yuko Saeki

4

1 reference

29 July 2017

Takashi Nakakuki

5

1 reference

29 July 2017

Takashi Naka

6

1 reference

29 July 2017

Hiroshi Tanaka

7

1 reference

29 July 2017

Shih-Feng Tsai

8

1 reference

29 July 2017

Mariko Okada-Hatakeyama

9

1 reference

29 July 2017

18 February 2011

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29 July 2017

1 reference

29 July 2017

5

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29 July 2017

29

1 reference

https://scigraph.springernature.com/pub.10.1186/1752-0509-5-29

29 July 2017

0 references

cites work

Mutation of epidermal growth factor receptor is associated with MIG6 expression

1 reference

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Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS

28 July 2018

1 reference

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Topological analysis of MAPK cascade for kinetic ErbB signaling

28 July 2018

1 reference

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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

28 July 2018

1 reference

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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

28 July 2018

1 reference

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Mechanisms for oncogenic activation of the epidermal growth factor receptor

28 July 2018

1 reference

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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The epidermal growth factor receptor pathway: a model for targeted therapy

28 July 2018

1 reference

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Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

EGF-ERBB signalling: towards the systems level

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Evidence that MIG-6 is a tumor-suppressor gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

In-frame deletion in the EGF receptor alters kinase inhibition by gefitinib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor (EGFR) signaling in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

ERBB receptors and cancer: the complexity of targeted inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

A small molecule-kinase interaction map for clinical kinase inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Multicomponent therapeutics for networked systems

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor inhibition strategies in oncology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

GAP control: regulating the regulators of small GTPases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Systematic quantification of gene interactions by phenotypic array analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Computational modeling of the EGF-receptor system: a paradigm for systems biology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The role of EGF-R expression on patient survival in lung cancer: a systematic review with meta-analysis

28 July 2018

1 reference

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

28 July 2018

1 reference

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Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

28 July 2018

1 reference

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Signaling via Shc family adapter proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

EGFR and cancer prognosis

28 July 2018

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

28 July 2018

1 reference

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Untangling the ErbB signalling network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The ErbB signaling network: receptor heterodimerization in development and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The structural basis of the activation of Ras by Sos

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Regulation of c-myc expression by Ras/Raf signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Two EGF molecules contribute additively to stabilization of the EGFR dimer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Association of p120 ras GAP with endocytic components and colocalization with epidermal growth factor (EGF) receptor in response to EGF stimulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Determinants of substrate recognition in the protein-tyrosine phosphatase, PTP1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Activation of Ras by receptor tyrosine kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Signal transduction by allosteric receptor oligomerization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The epidermal growth factor receptor phosphorylates GTPase-activating protein (GAP) at Tyr-460, adjacent to the GAP SH2 domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Insulin receptor and epidermal growth factor receptor dephosphorylation by three major rat liver protein-tyrosine phosphatases expressed in a recombinant bacterial system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Epidermal growth factor receptor: mechanisms of activation and signalling.

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Conspiracy theory: RAS and RAF do not act alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

The impact of the regulatory design on the response of epidermal growth factor receptor-mediated signal transduction towards oncogenic mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Simulation of crosstalk between small GTPase RhoA and EGFR-ERK signaling pathway via MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Mechanisms of regulating the Raf kinase family

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224393

Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells

29 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-5-29

Epidermal growth factor receptor overexpression correlates with a poor prognosis in completely resected non-small-cell lung cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21333004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Model analysis of difference between EGF pathway and FGF pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21333004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21333004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1752-0509-5-29

1 reference

journals/bmcsb/NaruoNUSNNTTO11

29 July 2017

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

29 July 2017

1 reference