In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening (Q33811917)

29 July 2017

In search of allosteric modulators of a7-nAChR by solvent density guided virtual screening (English)

1 reference

29 July 2017

Raja Dey

1

1 reference

PubMed ID

21294583

29 July 2017

Lin Chen

series ordinal

2

1 reference

29 July 2017

1 April 2011

1 reference

Journal of Biomolecular Structure and Dynamics

29 July 2017

1 reference

29 July 2017

28

1 reference

29 July 2017

695-715

1 reference

29 July 2017

5

1 reference

The Ligand Gated Ion Channel Database

29 July 2017

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic receptors at the amino acid level

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Emerging structure of the nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Subunit composition, distribution and function of GABA(A) receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Molecular structure and function of the glycine receptor chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Neuronal nicotinic receptors in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic receptor subtypes and cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotine and nicotinic receptor involvement in neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic receptors and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic acetylcholine receptors as targets for antidepressants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic acetylcholine receptors: from structure to brain function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic involvement in memory function in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Schizophrenia, sensory gating, and nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nicotinic acetylcholine receptors and the regulation of neuronal signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Treating schizophrenia symptoms with an alpha7 nicotinic agonist, from mice to men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

The novel alpha7 nicotinic acetylcholine receptor agonist N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-7-[2-(methoxy)phenyl]-1-benzofuran-2-carboxamide improves working and recognition memory in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

JN403, in vitro characterization of a novel nicotinic acetylcholine receptor alpha7 selective agonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetize

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Discovery of the alpha7 nicotinic acetylcholine receptor agonists. (R)-3'-(5-Chlorothiophen-2-yl)spiro-1-azabicyclo[2.2.2]octane-3,5'-[1',3']oxazolidin-2'-one as a novel, potent, selective, and orally bioavailable ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Allosteric modulation of nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

A new benzodiazepine pharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

5-Hydroxyindole potentiates human alpha 7 nicotinic receptor-mediated responses and enhances acetylcholine-induced glutamate release in cerebellar slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Potentiation of alpha7-containing nicotinic acetylcholine receptors by select albumins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Bioactivity of a peptide derived from acetylcholinesterase: involvement of an ivermectin-sensitive site on the alpha 7 nicotinic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Pocketome via comprehensive identification and classification of ligand binding envelopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Sequence analysis, structure prediction, and functional validation of phaC1/phaC2 genes of Pseudomonas sp. LDC-25 and its importance in polyhydroxyalkanoate accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Molecular modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Molecular modeling studies of the interaction between Plasmodium falciparum HslU and HslV subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Homology modeling of GLUT4, an insulin regulated facilitated glucose transporter and docking studies with ATP and its inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Function prediction of Rv0079, a hypothetical Mycobacterium tuberculosis DosR regulon protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Structural model of the pre-pore ring-like structure of Panton-Valentine leukocidin: providing dimensionality to biophysical and mutational data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Molecular modeling of Mycobacterium tuberculosis DNA gyrase and its molecular docking study with gatifloxacin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Homology modeling of Cry10Aa toxin from B. thuringiensis israelensis and B. thuringiensis subsp. LDC-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Homology modeling and docking studies of human Bcl-2L10 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

A docking study using atomistic conformers generated via elastic network model for cyclosporin A/cyclophilin A complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Computational model of the HIV-1 subtype A V3 loop: study on the conformational mobility for structure-based anti-AIDS drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Structure and dynamics of double helical DNA in torsion angle hyperspace: a molecular mechanics approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Docking simulation and competitive experiments validate the interaction between the 2,5-xylidine inhibitor and Rigidoporus lignosus laccase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Computational studies of human galectin-1: role of conserved tryptophan residue in stacking interaction with carbohydrate ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Construction and assessment of reaction models of class I EPSP synthase: molecular docking and density functional theoretical calculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Computational study of the sulfonylated amino acid hydroxamates binding to the zinc ion within the active site of carbonic anhydrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Weighted equation and rules--a novel concept for evaluating protein-ligand interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Virtual screening and drug design for PDE-5 receptor from traditional Chinese medicine database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Ligand-based dual target drug design for H1N1: swine flu--a preliminary first study

21 January 2018

1 reference

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Structure-based and ligand-based drug design for HER 2 receptor

21 January 2018

1 reference

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A novel strategy for designing the selective PPAR agonist by the "sum of activity" model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Selective optimization of side activities: another way for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

DrugBank: a knowledgebase for drugs, drug actions and drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508600

PPT-DB: the protein property prediction and testing database.

21 January 2018

1 reference

5 May 2024

https://opencitations.net/index/api/v1/citations/10.1093/NAR/GKM800

Identifiers

DOI

10.1080/07391102.2011.10508600

1 reference

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Fatcat ID

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Fatcat

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