Cross-regulation between oncogenic BRAF(V600E) kinase and the MST1 pathway in papillary thyroid carcinoma (Q33797782)

29 July 2017

Cross-regulation between oncogenic BRAF(V600E) kinase and the MST1 pathway in papillary thyroid carcinoma (English)

1 reference

29 July 2017

papillary thyroid cancer

1 reference

Dae-Sik Lim

14

0 references

author name string

Seong Jin Lee

1

1 reference

29 July 2017

Min Hee Lee

2

1 reference

29 July 2017

Dong Wook Kim

3

1 reference

29 July 2017

Seongeun Lee

4

1 reference

29 July 2017

Songmei Huang

5

1 reference

29 July 2017

Min Jeong Ryu

6

1 reference

29 July 2017

Yong Kyung Kim

7

1 reference

29 July 2017

Sung Jin Kim

8

1 reference

29 July 2017

Soung Jung Kim

9

1 reference

29 July 2017

Jung Hwan Hwang

10

1 reference

29 July 2017

Sangphil Oh

11

1 reference

29 July 2017

Heeyeong Cho

12

1 reference

29 July 2017

Jin Man Kim

13

1 reference

29 July 2017

Young Suk Jo

15

1 reference

29 July 2017

Minho Shong

16

1 reference

29 July 2017

language of work or name

English

0 references

publication date

13 January 2011

1 reference

29 July 2017

1 reference

29 July 2017

6

1 reference

29 July 2017

e16180

1 reference

29 July 2017

1

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

start time

13 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3020965/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

28 July 2018

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Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse

28 July 2018

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Identification of direct transcriptional targets of (V600E)BRAF/MEK signalling in melanoma

28 July 2018

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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

28 July 2018

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Structure/function relationships underlying regulation of FOXO transcription factors

28 July 2018

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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

28 July 2018

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Highly methylated genes in colorectal neoplasia: implications for screening

28 July 2018

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The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1

28 July 2018

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Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation

28 July 2018

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Stressing the role of FoxO proteins in lifespan and disease

28 July 2018

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Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway

28 July 2018

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The integration of signaling by multiprotein complexes containing Raf kinases

28 July 2018

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A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

28 July 2018

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Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

28 July 2018

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RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumors

28 July 2018

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Quantitative assessment of promoter methylation profiles in thyroid neoplasms.

28 July 2018

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Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

28 July 2018

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Taming the Hippo: Raf-1 controls apoptosis by suppressing MST2/Hippo

28 July 2018

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Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

28 July 2018

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The RAF proteins take centre stage

28 July 2018

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Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.

28 July 2018

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The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

28 July 2018

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Clinical implication of hot spot BRAF mutation, V599E, in papillary thyroid cancers

28 July 2018

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

28 July 2018

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

28 July 2018

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Mutations of the BRAF gene in human cancer

28 July 2018

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

28 July 2018

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Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

28 July 2018

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Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

28 July 2018

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Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells

21 January 2018

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Regulation of FoxO activity by CBP/p300-mediated acetylation.

21 January 2018

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Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

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The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

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BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis

21 January 2018

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BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications

21 January 2018

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NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis

21 January 2018

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Influence of the BRAF V600E mutation on expression of vascular endothelial growth factor in papillary thyroid cancer.

30 October 2018

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Regulation of protein kinase B tyrosine phosphorylation by thyroid-specific oncogenic RET/PTC kinases

30 October 2018

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High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020965

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020965

Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020965

MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020965

Negative regulation of the forkhead transcription factor FKHR by Akt.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020965

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation

30 October 2018

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12 December 2020

Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features

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12 December 2020

Suppression of BRAF(V599E) in human melanoma abrogates transformation

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12 December 2020

Lack of association between BRAF mutation and MAPK ERK activation in melanocytic nevi

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12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

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12 December 2020

BRAF Mutation in Papillary Thyroid Carcinoma

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12 December 2020

Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features

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12 December 2020

10.1371/JOURNAL.PONE.0016180

Identifiers

DOI

1 reference

29 July 2017

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29 July 2017

1 reference