In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted. (Q33782356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9499056%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted (English)

1 reference

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10 November 2019

1 reference

M Lusky

1

1 reference

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10 November 2019

M Christ

2

1 reference

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10 November 2019

K Rittner

3

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10 November 2019

A Dieterle

4

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10 November 2019

D Dreyer

5

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10 November 2019

B Mourot

6

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10 November 2019

H Schultz

7

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10 November 2019

F Stoeckel

8

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10 November 2019

A Pavirani

9

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10 November 2019

M Mehtali

10

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10 November 2019

language of work or name

1 reference

1 March 1998

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10 November 2019

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10 November 2019

volume

72

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10 November 2019

page(s)

2022-2032

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10 November 2019

issue

3

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Manipulation of adenovirus vectors

10 November 2019

cites work

1 reference

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Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression

4 July 2018

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Persistent transgene expression in mouse liver following in vivo gene transfer with a delta E1/delta E4 adenovirus vector

4 July 2018

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Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response

4 July 2018

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Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors.

4 July 2018

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Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors.

4 July 2018

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Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo

4 July 2018

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Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses

4 July 2018

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Conditional repression of the E2 transcription unit in E1-E3-deleted adenovirus vectors is correlated with a strong reduction in viral DNA replication and late gene expression in vitro

4 July 2018

1 reference

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Effect of the E4 region on the persistence of transgene expression from adenovirus vectors.

4 July 2018

1 reference

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Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy.

4 July 2018

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Oncogenic potential of the adenovirus E4orf6 protein

4 July 2018

1 reference

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Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo

4 July 2018

1 reference

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Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted

4 July 2018

1 reference

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Adenovirus-pulsed dendritic cells stimulate human virus-specific T-cell responses in vitro.

4 July 2018

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A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions

4 July 2018

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A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4.

4 July 2018

1 reference

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Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues

4 July 2018

1 reference

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Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.

4 July 2018

1 reference

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Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants

4 July 2018

1 reference

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Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs

4 July 2018

1 reference

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Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

4 July 2018

1 reference

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Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit

4 July 2018

1 reference

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Adenovirus early region 4 and viral DNA synthesis

4 July 2018

1 reference

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Assessment of recombinant adenoviral vectors for hepatic gene therapy

4 July 2018

1 reference

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Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

4 July 2018

1 reference

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Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli

4 July 2018

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Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver

4 July 2018

1 reference

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Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

4 July 2018

1 reference

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Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

4 July 2018

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Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a.

4 July 2018

1 reference

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Transcriptional activation by tetracyclines in mammalian cells

4 July 2018

1 reference

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The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer

4 July 2018

1 reference

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In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

4 July 2018

1 reference

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A severe combined immunodeficiency mutation in the mouse

4 July 2018

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The region of mouse mammary tumor virus DNA containing the long terminal repeat includes a long coding sequence and signals for hormonally regulated transcription

4 July 2018

1 reference

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A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2

4 July 2018

1 reference

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A new technique for the assay of infectivity of human adenovirus 5 DNA

4 July 2018

1 reference

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A simple salting out procedure for extracting DNA from human nucleated cells

4 July 2018

1 reference

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Development of adenovirus vectors for the expression of heterologous genes

4 July 2018

1 reference

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Redundant control of adenovirus late gene expression by early region 4

4 July 2018

1 reference

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Plasmid and bacteriophage vectors for excision of intact inserts

4 July 2018

1 reference

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The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2

4 July 2018

1 reference

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Widespread long-term gene transfer to mouse skeletal muscles and heart

4 July 2018

1 reference

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Construction, characterization, and utilization of cell lines which inducibly express the adenovirus DNA-binding protein

4 July 2018

1 reference

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Characteristics of a human cell line transformed by DNA from human adenovirus type 5

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

4 July 2018

1 reference

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Sustained expression of therapeutic levels of human factor VIII in mice

30 October 2018

1 reference

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Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice

30 October 2018

1 reference

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30 October 2018

1 reference

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Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109495

Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.

30 October 2018

1 reference

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Deletion mutants of adenovirus 2: Isolation and initial characterization of virus carrying mutations near the right end of the viral genome

30 October 2018

1 reference

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Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9499056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Persistence of Replication-Deficient Adenovirus-Mediated Gene Transfer in Lungs of Immune-Deficient (nu/nu) Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9499056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9499056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9499056%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference