Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer. (Q33766192)

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English	Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer.	scientific article

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19 January 2020

Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer (English)

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19 January 2020

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Jitka Soukupova

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19 January 2020

Andrea Brancale

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19 January 2020

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Ghali Brahemi

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19 January 2020

Fathima R Kona

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19 January 2020

Annalisa Fiasella

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19 January 2020

Daniela Buac

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19 January 2020

Angelika M Burger

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19 January 2020

Andrew D Westwell

8

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19 January 2020

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1 April 2010

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19 January 2020

Journal of Medicinal Chemistry

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19 January 2020

53

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19 January 2020

7

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19 January 2020

2757-2765

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19 January 2020

Role of the BCA2 ubiquitin E3 ligase in hormone responsive breast cancer

1 reference

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22 June 2018

Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

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Involvement of Rabring7 in EGF receptor degradation as an E3 ligase

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22 June 2018

Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism

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Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients

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22 June 2018

Novel RING E3 ubiquitin ligases in breast cancer

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22 June 2018

Disulfiram, an old drug with new potential therapeutic uses for human cancers and fungal infections

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22 June 2018

Drug discovery in the ubiquitin-proteasome system.

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22 June 2018

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

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22 June 2018

A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer

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22 June 2018

Inhibition of proteasome activity, nuclear factor-KappaB translocation and cell survival by the antialcoholism drug disulfiram

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22 June 2018

The ubiquitin-mediated protein degradation pathway in cancer: therapeutic implications

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22 June 2018

Development of the proteasome inhibitor Velcade (Bortezomib).

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22 June 2018

The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1).

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22 June 2018

RING finger proteins: mediators of ubiquitin ligase activity

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22 June 2018

Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism

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22 June 2018

The ubiquitin system

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22 June 2018

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22 June 2018

The effect of some analogues of disulfiram on the aldehyde dehydrogenases of sheep liver

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22 June 2018

The effect of disulfiram on the aldehyde dehydrogenases of sheep liver

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Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).

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Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells

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Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity.

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One-pot synthesis of dithiocarbamates accelerated in water.

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A Short, Novel, and Cheaper Procedure for Oligonucleotide Synthesis Using Automated Solid Phase Synthesizer

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Inactivation of the human papillomavirus-16 E6 oncoprotein by organic disulfides.

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Straightforward and Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions

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12 December 2020

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Induction of apoptosis by thiuramdisulfides, the reactive metabolites of dithiocarbamates, through coordinative modulation of NFkappaB, c-fos/c-jun, and p53 proteins

1 reference

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Novel alternative for the N-S bond formation and its application to the synthesis of benzisothiazol-3-ones

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12 December 2020

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10.1021/JM901757T

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19 January 2020

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19 January 2020

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19 January 2020

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