Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling (Q33735931)

29 July 2017

Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling (English)

1 reference

29 July 2017

0 references

10

Stuart J Frank

1 reference

29 July 2017

Yujun Gan

1

1 reference

29 July 2017

Yue Zhang

2

1 reference

29 July 2017

Douglas J Digirolamo

3

1 reference

29 July 2017

Jing Jiang

4

1 reference

29 July 2017

Xiangdong Wang

5

1 reference

29 July 2017

Xuemei Cao

6

1 reference

29 July 2017

Kurt R Zinn

7

1 reference

29 July 2017

David P Carbone

8

1 reference

29 July 2017

Thomas L Clemens

9

1 reference

29 July 2017

4 February 2010

1 reference

29 July 2017

Molecular Endocrinology

1 reference

29 July 2017

24

1 reference

29 July 2017

3

1 reference

29 July 2017

644-656

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2840807/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A novel unidirectional cross-talk from the insulin-like growth factor-I receptor to leptin receptor in human breast cancer cells

21 June 2018

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JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells

21 June 2018

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Growth hormone, insulin-like growth factors, and the skeleton

21 June 2018

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Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: a novel mechanism for GH insensitivity

21 June 2018

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Dual silencing of the EGF and type 1 IGF receptors suggests dominance of IGF signaling in human breast cancer cells

21 June 2018

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A mutant signal transducer and activator of transcription 5b, associated with growth hormone insensitivity and insulin-like growth factor-I deficiency, cannot function as a signal transducer or transcription factor

21 June 2018

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Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction

21 June 2018

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Insulin enhances growth hormone induction of the MEK/ERK signaling pathway

21 June 2018

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Growth hormone alters epidermal growth factor receptor binding affinity via activation of extracellular signal-regulated kinases in 3T3-F442A cells

21 June 2018

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

21 June 2018

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Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements

21 June 2018

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A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

21 June 2018

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Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling

21 June 2018

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Circulating levels of IGF-1 directly regulate bone growth and density

21 June 2018

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Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)

21 June 2018

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Receptor dimerization in GH and erythropoietin action--it takes two to tango, but how?

21 June 2018

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Distinct and overlapping functions of insulin and IGF-I receptors

21 June 2018

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Growth hormone-regulated intracellular signaling in UMR 106 osteosarcoma cells

21 June 2018

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Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

21 June 2018

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Activation of the Jak/Stat signal transduction pathway in GH-treated rat osteoblast-like cells in culture

21 June 2018

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Growth hormone axis overview--somatomedin hypothesis

21 June 2018

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The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes

21 June 2018

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Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts

21 June 2018

1 reference

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Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH-induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization

21 June 2018

1 reference

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Growth hormone stimulates tyrosine phosphorylation of focal adhesion kinase (p125(FAK)) and actin stress fiber formation in human osteoblast-like cells, Saos2.

21 June 2018

1 reference

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Normal growth and development in the absence of hepatic insulin-like growth factor I

21 June 2018

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

21 June 2018

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Interactions between growth hormone, insulin-like growth factor I, and basic fibroblast growth factor in melanocyte growth

21 June 2018

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Insulin receptor substrate-1 enhances growth hormone-induced proliferation

21 June 2018

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Insulin and insulin-like growth factor-I receptor mediated differentiation of 3T3-F442A cells into adipocytes: effect of PI 3-kinase inhibition.

21 June 2018

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Binding of STAT5a and STAT5b to a single element resembling a gamma-interferon-activated sequence mediates the growth hormone induction of the mouse acid-labile subunit promoter in liver cells

21 June 2018

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Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

21 June 2018

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Insulin-like growth factor I inhibits the transcription of collagenase 3 in osteoblast cultures

21 June 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 June 2018

1 reference

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Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation

21 June 2018

1 reference

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Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

21 June 2018

1 reference

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Molecular mechanism of growth hormone action

21 June 2018

1 reference

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The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

21 June 2018

1 reference

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Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

21 June 2018

1 reference

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Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Identification of growth hormone receptors on human growth plate chondrocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Distinct cytoplasmic regions of the growth hormone receptor are required for activation of JAK2, mitogen-activated protein kinase, and transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone stimulates proliferation of normal human bone marrow stromal osteoblast precursor cells in vitro.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone stimulates proliferation and differentiation of normal human osteoblast-like cells in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Mode of action of pituitary growth hormone on target cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

The ontogeny of growth hormone receptors in the rabbit tibia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Phosphorylation of highly purified growth hormone receptors by a growth hormone receptor-associated tyrosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Structural design and molecular evolution of a cytokine receptor superfamily

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Insulin-like growth factor-I and insulin-like growth factor-II induce c-fos in mouse osteoblastic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone synergizes with serum growth factors in inducing c-fos transcription in 3T3-F442A cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth hormone (GH) induction of tyrosine phosphorylation and activation of mitogen-activated protein kinases in cells transfected with rat GH receptor cDNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Mode of growth hormone action in osteoblasts.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

In vivo imaging of hepatic growth hormone signaling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

The skeletal structure of insulin-like growth factor I-deficient mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

STAT5b is required for GH-induced liver IGF-I gene expression.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Effects of Igf1 gene deletion on postnatal growth patterns.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840807

Growth Hormone Induction of Hepatic Serine Protease Inhibitor 2.1 Transcription Is Mediated by a Stat5-related Factor Binding Synergistically to Two γ-Activated Sites

30 October 2018

1 reference

12 December 2020

Expression of functional growth hormone receptors in cultured human osteoblast-like cells

1 reference

12 December 2020

Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

1 reference

12 December 2020

Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor

1 reference

12 December 2020

Growth hormone binds to a single high affinity receptor site on mouse osteoblasts: modulation by retinoic acid and cell differentiation

1 reference

12 December 2020

Estrogen enhances growth hormone receptor expression and growth hormone action in rat osteosarcoma cells and human osteoblast-like cells

1 reference

12 December 2020

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

1 reference

12 December 2020

Growth hormone insensitivity associated with a STAT5b mutation

1 reference

12 December 2020

Postnatal body growth is dependent on the transcription factors signal transducers and activators of transcription 5a/b in muscle: a role for autocrine/paracrine insulin-like growth factor I

1 reference

12 December 2020

Growth hormone, insulin-like growth factor I, and growth: local knowledge

1 reference

12 December 2020

Insulin-like growth factor I is essential for postnatal growth in response to growth hormone

1 reference

12 December 2020

STAT5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver

1 reference

12 December 2020

Insulin-like growth factor I receptor signaling--overlapping or redundant pathways?

1 reference

12 December 2020

Growth hormone is mitogenic for fetal mouse osteoblasts but not for undifferentiated bone cells

1 reference

12 December 2020

Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2009-0357

1 reference

29 July 2017

1 reference

29 July 2017

1 reference