In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase (Q42799629)

7 November 2017

In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase (English)

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7 November 2017

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Carlos García-Echeverría

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7 November 2017

Mark A Pearson

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7 November 2017

Andreas Marti

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7 November 2017

Thomas Meyer

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Juergen Mestan

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Johann Zimmermann

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7 November 2017

Jiaping Gao

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7 November 2017

Josef Brueggen

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7 November 2017

Hans-Georg Capraro

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7 November 2017

Robert Cozens

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7 November 2017

Dean B Evans

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Doriano Fabbro

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Pascal Furet

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Diana Graus Porta

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7 November 2017

Janis Liebetanz

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Georg Martiny-Baron

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7 November 2017

Stephan Ruetz

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Francesco Hofmann

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1 March 2004

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231-239

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describes a project that uses

7 November 2017

NWT-21

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cdc2 is a component of the M phase-specific histone H1 kinase: evidence for identity with MPF

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7 January 2021

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7 January 2021

The contradictions of the insulin-like growth factor 1 receptor

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7 January 2021

Bcr/Abl expression stimulates integrin function in hematopoietic cell lines

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7 January 2021

Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo

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7 January 2021

Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo.

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7 January 2021

A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

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7 January 2021

Insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the platelet-derived growth factor receptor

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7 January 2021

Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells

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7 January 2021

Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

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Insulin-like growth factors and cancer

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Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents

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7 January 2021

Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis

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7 January 2021

Expression of a kinase-deficient IGF-I-R suppresses tumorigenicity of rhabdomyosarcoma cells constitutively expressing a wild type IGF-I-R

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7 January 2021

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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The effects of insulin-like growth factors on tumorigenesis and neoplastic growth

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Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis

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7 January 2021

Large-scale purification and characterisation of a recombinant epidermal growth-factor receptor protein-tyrosine kinase. Modulation of activity by multiple factors

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Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors.

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Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant

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7 January 2021

Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras

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7 January 2021

Inhibition of carcinoma cell growth and metastasis by a vesicular stomatitis virus G-pseudotyped retrovector expressing type I insulin-like growth factor receptor antisense

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7 January 2021

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

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Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

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7 January 2021

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

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7 January 2021

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

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7 January 2021

Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma

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7 January 2021

Expression of protein kinase C isotypes using baculovirus vectors.

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7 January 2021

Dual control of cell growth by somatomedins and platelet-derived growth factor

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7 January 2021

Signal transduction by receptors with tyrosine kinase activity

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7 January 2021

Insulin-like growth factor I receptor signaling in transformation by src oncogenes

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7 January 2021

Insulin-like growth factor receptor-1 as an anti-cancer target: blocking transformation and inducing apoptosis

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7 January 2021

Antisense inhibition of IGF receptor expression in HaCaT keratinocytes: a model for antisense strategies in keratinocytes

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7 January 2021

Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase

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7 January 2021

Role of the insulin-like growth factor family in cancer development and progression

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7 January 2021

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Identifiers

DOI

1 reference

release_nsjho2zxmfherjkgunxblua42e

7 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nsjho2zxmfherjkgunxblua42e

24 November 2022

mapped directly with Wikidata item

1 reference