PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease (Q33734125)

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English	PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

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Europe PubMed Central

PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease (English)

1 reference

Europe PubMed Central

29 July 2017

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fatty liver disease

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Douglas Osei-Hyiaman

object named as

Douglas Osei-Hyiaman

2

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author name string

James P Hardwick

1

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Europe PubMed Central

29 July 2017

Homer Wiland

3

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Europe PubMed Central

29 July 2017

Mohamed A Abdelmegeed

4

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Europe PubMed Central

29 July 2017

Byoung-Joon Song

5

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Europe PubMed Central

29 July 2017

language of work or name

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based on heuristic

inferred from title

publication date

1 January 2009

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

2009

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Europe PubMed Central

29 July 2017

952734

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Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2009

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April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

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Recent concepts in non-alcoholic fatty liver disease

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Cytochrome P450 and liver diseases

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Decreased Hepatic Triglyceride Accumulation and Altered Fatty Acid Uptake in Mice with Deletion of the Liver Fatty Acid-binding Protein Gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

The many roles of cytochrome b5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Drug-induced phospholipidosis: are there functional consequences?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Alternative splicing determines the function of CYP4F3 by switching substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Regulation of CYP4F2 leukotriene B4 omega-hydroxylase by retinoic acids in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Promoter activity and regulation of the CYP4F2 leukotriene B(4) omega-hydroxylase gene by peroxisomal proliferators and retinoic acid in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. Implications for peroxisome proliferator-activated receptor alpha natural ligand metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Transcriptional activation by amphipathic carboxylic peroxisomal proliferators is induced by the free acid rather than the acyl-CoA derivative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Metabolic aspects of peroxisomal beta-oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

21 June 2018

Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Effects of intravenous triacylglycerol emulsions on hepatic metabolism and blood metabolites in fasted dairy cows

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Diet-induced obesity and hepatic steatosis in L-Fabp / mice is abrogated with SF, but not PUFA, feeding and attenuated after cholesterol supplementation

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

The gene encoding acyl-CoA-binding protein is subject to metabolic regulation by both sterol regulatory element-binding protein and peroxisome proliferator-activated receptor alpha in hepatocytes

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Stability of fatty acyl-coenzyme A thioester ligands of hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Suppression of hepatocyte nuclear factor-4alpha by acyl-CoA thioesters of hypolipidemic peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Disordered Fat Storage and Mobilization in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Metformin and insulin meet in a most atypical way.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Liver fat and lipid oxidation in humans.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Specialized hepatocyte-like cells regulate Drosophila lipid metabolism.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Cyp4a14 overexpression induced by hyperoxia in female CBA mice as a possible contributor of increased resistance to oxidative stress.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

Temporal pattern of de novo lipogenesis in the postprandial state in healthy men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840373

30 October 2018

Effects of steatosis on drug-metabolizing capability of primary human hepatocytes

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F952734

21 January 2018

CYP2E1 is not involved in early alcohol-induced liver injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of alcoholic liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma and retinoid X receptor signaling regulate fatty acid uptake by primary human placental trophoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome Proliferator-Activated Receptor α Protects against Obesity-Induced Hepatic Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance: 1996 update

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of differences in fatty acid metabolism between obese and non-obese patients with non-alcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonalcoholic steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The liver in celiac disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypolipidemic effect of peroxisome proliferators. Transcriptional suppression of apolipoprotein C-III

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free acetate production by rat hepatocytes during peroxisomal fatty acid and dicarboxylic acid oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARalpha in the pathogenesis of fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Omega-oxidation of very long-chain fatty acids in human liver microsomes. Implications for X-linked adrenoleukodystrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochromes P450, oxygen, and evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal fatty acid metabolism, peroxisomal proliferator-activated receptors and non-alcoholic fatty liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation kinetics of ethanol by human cytochrome P450 2E1. Rate-limiting product release accounts for effects of isotopic hydrogen substitution and cytochrome b5 on steady-state kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20300478

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2009/952734

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

ResearchGate publication ID

0 references

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