The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). (Q36328530)

13 August 2017

1 reference

title

The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). (English)

1 reference

13 August 2017

Marjorie A Peraza

1

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13 August 2017

Andrew D Burdick

2

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13 August 2017

Holly E Marin

3

1 reference

13 August 2017

Frank J Gonzalez

4

1 reference

13 August 2017

Jeffrey M Peters

5

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13 August 2017

1 December 2005

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13 August 2017

Toxicological Sciences

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13 August 2017

90

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13 August 2017

269-295

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13 August 2017

2

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Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet.

13 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Risk of adverse events with fibrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Biliary lipid composition during treatment with different hypolipidaemic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Fenofibrate. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in dyslipidaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR gamma is required for placental, cardiac, and adipose tissue development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Fenofibrate monotherapy induced rhabdomyolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-gamma agonists suppress adrenocortical tumor cell proliferation and induce differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Adiponectin: a relevant player in PPARgamma-agonist-mediated improvements in hepatic insulin sensitivity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Complications during clofibrate treatment of nephrotic-syndrome hyperlipoproteinaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Fenofibrate impairs rat mitochondrial function by inhibition of respiratory complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Studies of synergistic and antagonistic combinations of conventional cytotoxic agents with the multiple eicosanoid pathway modulator LY 293111.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Role of fibrates and HMG-CoA reductase inhibitors in gallstone formation: epidemiological study in an unselected population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARdelta is a very low-density lipoprotein sensor in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Ciglitazone induces early cellular proliferation and NF-kappaB transcriptional activity in colon cancer cells through p65 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase sign

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma activation induces cell cycle arrest via the p53-independent pathway in human anaplastic thyroid cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Di-(2-ethylhexyl) phthalate suppresses estradiol and ovulation in cycling rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Cardiac teratogenesis of trichloroethylene and dichloroethylene in a mammalian model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Cardiac teratogenesis of halogenated hydrocarbon-contaminated drinking water

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptors: nuclear control of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Design and synthesis of N-[(4-methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a novel peroxisome proliferator-activated receptor alpha/gamma dual agonist with efficacious gluco

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Troglitazone induces CYP3A4 activity leading to falsely abnormal dexamethasone suppression test

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Phosphorylation of PPARs: from molecular characterization to physiological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Hic-5 regulates an epithelial program mediated by PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Induction of PPARbeta and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARbeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor delta as a molecular target to regulate lung cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic xenobiotic metabolizing and antioxidant enzymes in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of mitogen-activated protein kinases by peroxisome proliferator-activated receptor ligands: an example of nongenomic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

APC-dependent suppression of colon carcinogenesis by PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Rhabdomyolysis and acute renal failure associated with bezafibrate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Prostacyclin-dependent apoptosis mediated by PPAR delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR-gamma receptor ligands: novel therapy for pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Functional PPAR-gamma receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Myopathy and rhabdomyolysis with lipid-lowering drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Down-regulation of peroxisome proliferator-activated receptor gamma in human cervical carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A case of rosiglitazone exposure in the second trimester of pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Bezafibrate induced rhabdomyolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Induction of differentiation and peroxisome proliferator-activated receptor gamma expression in colon cancer cell lines by troglitazone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-gamma activation inhibits tumor progression in non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARbeta/delta selectively induces differentiation and inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARalpha agonist-induced rodent tumors: modes of action and human relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Acute Muscular Syndrome Associated with Administration of Clofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The developmental toxicity of perfluoroalkyl acids and their derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Rhabdomyolysis and renal failure associated with gemfibrozil monotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of PPARdelta alters lipid metabolism in db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Involvement of c‐jun N‐terminal kinase activation in 15‐deoxy‐δ12,14‐prostaglandin J2–and prostaglandin A1–induced apoptosis in AGS gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Trichloroethylene: a cardiac teratogen in developing chick embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Growth dynamics of human leiomyoma cells and inhibitory effects of the peroxisome proliferator-activated receptor-gamma ligand, pioglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Troglitazione affects survival of human osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor alpha target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The mitochondrial respiratory complex I is a target for 15-deoxy-delta12,14-prostaglandin J2 action

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

High ovulatory rates with use of troglitazone in clomiphene-resistant women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptors and hepatic stellate cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Terminal differentiation of human breast cancer through PPAR gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-γ ligand rosiglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator activator receptors (PPAR), insulin resistance, and cardiomyopathy: friends or foes for the diabetic patient with heart failure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Molecular design, synthesis, and hypoglycemic activity of a series of thiazolidine-2,4-diones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Dimethoxyethyl phthalate: embryopathy, teratogenicity, fetal metabolism and the role of zinc in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-alpha and liver cancer: where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effect of phthalate esters on reproduction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Promotion of colon tumors in C57BL/6J-APC(min)/+ mice by thiazolidinedione PPARgamma agonists and a structurally unrelated PPARgamma agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The effect of PPAR?? ligands on the proliferation and apoptosis of human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Biliary lipids, lithogenic index and biliary drug concentrations during etofibrate and bezafibrate treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor γ in diabetes and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Lysophosphatidic acid attenuates the cytotoxic effects and degree of peroxisome proliferator-activated receptor gamma activation induced by 15-deoxyDelta12,14-prostaglandin J2 in neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Growth inhibition of esophageal squamous carcinoma cells by peroxisome proliferator-activated receptor-gamma ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Clofibrate myopathy: a case report and a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

A novel peroxisome proliferator-activated receptor gamma isoform with dominant negative activity generated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPAR delta agonists stimulate oligodendrocyte differentiation in tissue culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Hepatic stellate cells: unique characteristics in cell biology and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Bezafibrate Induces a Mitochondrial Derangement in Human Cell Lines: A PPAR-Independent Mechanism for a Peroxisome Proliferator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Enhancement of antitumor activity of docetaxel by celecoxib in lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effect of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of lung tumors and their expression of cyclooxygenase-2 and peroxisome proliferator- activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma activation can regulate beta-catenin levels via a proteasome-mediated and adenomatous polyposis coli-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Recent advances in peroxisome proliferator-activated receptor science

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Teratogenicity of di(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

trans-activation of PPARalpha and induction of PPARalpha target genes by perfluorooctane-based chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Teratogenicity of Phthalate Esters in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Mutagenic and antifertility sensitivities of mice to di-2-ethylhexyl phthalate (DEHP) and dimethoxyethyl phthalate (DMEP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The synthetic ligand of peroxisome proliferator-activated receptor-gamma ciglitazone affects human glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor alpha in the human breast cancer cell lines MCF-7 and MDA-MB-231.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Critical roles of PPAR beta/delta in keratinocyte response to inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Studies of early hepatocellular proliferation and peroxisomal proliferation in Sprague-Dawley rats treated with tumorigenic doses of clofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

MEHP/DEHP: gonadal toxicity and effects on rodent accessory sex organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effects of troglitazone on HepG2 viability and mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Teratogenicity/fetotoxicity of DEHP in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Developmental toxicity evaluation of dietary di(2-ethylhexyl)phthalate in Fischer 344 rats and CD-1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Ligands for the peroxisome proliferator-activated receptor-gamma have inhibitory effects on growth of human neuroblastoma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The peroxisome proliferator activated receptor delta is required for the differentiation of THP-1 monocytic cells by phorbol ester

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effects of peroxisome proliferator-activated receptor alpha/delta agonists on HDL-cholesterol in vervet monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Regulation of muscle fiber type and running endurance by PPARdelta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Peroxisome proliferator-activated receptor gamma and metabolic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Maternal clofibrate administration amplifies fetal peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Formation of a novel quinone epoxide metabolite of troglitazone with cytotoxicity to HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effects of pioglitazone on calcium channels in vascular smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Collecting duct-specific deletion of peroxisome proliferator-activated receptor gamma blocks thiazolidinedione-induced fluid retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

The effect of peroxisome proliferators on mitochondrial bioenergetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Selective Expression of a Dominant-Negative Form of Peroxisome Proliferator-Activated Receptor in Keratinocytes Leads to Impaired Epidermal Healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFJ062

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/47254

15 July 2023

Identifiers

DOI

10.1093/TOXSCI/KFJ062

1 reference

13 August 2017

1 reference