Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells (Q33700607)

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English	Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells (English)

1 reference

Europe PubMed Central

28 July 2017

apoptotic process

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author name string

Nayoung Kim

1

1 reference

Europe PubMed Central

28 July 2017

Sami Kukkonen

2

1 reference

Europe PubMed Central

28 July 2017

Sumeet Gupta

3

1 reference

Europe PubMed Central

28 July 2017

Anna Aldovini

4

1 reference

Europe PubMed Central

28 July 2017

publication date

16 September 2010

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Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

6

1 reference

Europe PubMed Central

28 July 2017

e1001103

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Europe PubMed Central

28 July 2017

9

1 reference

Europe PubMed Central

28 July 2017

copyright license

Creative Commons Attribution 4.0 International

16 September 2010

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April 2022 Public Data File from Crossref

copyright status

0 references

c-Myc regulates transcriptional pause release

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21 June 2018

FOXO transcription factors enforce cell cycle checkpoints and promote survival of hematopoietic cells after DNA damage.

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21 June 2018

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

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The 48-kDa alternative translation isoform of PP2A:B56epsilon is required for Wnt signaling during midbrain-hindbrain boundary formation

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21 June 2018

Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A.

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21 June 2018

Tenets of PTEN tumor suppression

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21 June 2018

Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation

1 reference

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21 June 2018

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).

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21 June 2018

PP2A regulates the pro-apoptotic activity of FOXO1.

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21 June 2018

Transcription factor FOXO3a mediates apoptosis in HIV-1-infected macrophages

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Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies

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21 June 2018

Transcriptional regulation of Bim by FoxO3A mediates hepatocyte lipoapoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Chromatin immunoprecipitation and microarray-based analysis of protein location

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Emerging roles of nuclear protein phosphatases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Regulation of HIV-1 transcription by protein phosphatase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Identification of a tumour suppressor network opposing nuclear Akt function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

HIV-1 Tat interactions with p300 and PCAF transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through CREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell lines

1 reference

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21 June 2018

Mammalian SIRT1 represses forkhead transcription factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

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Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

1 reference

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A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes

1 reference

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Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Genome-wide location and function of DNA binding proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Modulation of Akt kinase activity by binding to Hsp90

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae

1 reference

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21 June 2018

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

HIV-1 Tat: coping with negative elongation factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Alterations of the PPP2R1B gene in human lung and colon cancer

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21 June 2018

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

The HIV-1 Tat nuclear localization sequence confers novel nuclear import properties

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21 June 2018

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

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21 June 2018

Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

Cellular uptake of the tat protein from human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

21 June 2018

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001103

21 January 2018

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001103

21 January 2018

PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001103

21 January 2018

Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001103

21 January 2018

Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940756

30 October 2018

Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20862322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of the Aalpha subunit of protein phosphatase 2A in human gliomas in the absence of mutations in the Aalpha and Abeta subunit genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20862322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1001103

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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