Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi (Q33689110)

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English	Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi	scientific article

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scholarly article

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Europe PubMed Central

28 July 2017

Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi (English)

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Europe PubMed Central

28 July 2017

object named as

Chen Chen

9

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author name string

Lai-Ling Du

1

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Europe PubMed Central

28 July 2017

Jia-Zhao Xie

2

1 reference

Europe PubMed Central

28 July 2017

Xiang-Shu Cheng

3

1 reference

Europe PubMed Central

28 July 2017

Xiao-Hong Li

4

1 reference

Europe PubMed Central

28 July 2017

Fan-Li Kong

5

1 reference

Europe PubMed Central

28 July 2017

Xia Jiang

6

1 reference

Europe PubMed Central

28 July 2017

Zhi-Wei Ma

7

1 reference

Europe PubMed Central

28 July 2017

Jian-Zhi Wang

8

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Europe PubMed Central

28 July 2017

Xin-Wen Zhou

10

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Europe PubMed Central

28 July 2017

publication date

20 October 2013

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Europe PubMed Central

28 July 2017

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Europe PubMed Central

28 July 2017

36

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Europe PubMed Central

28 July 2017

613-623

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Europe PubMed Central

28 July 2017

2

1 reference

Europe PubMed Central

28 July 2017

ERK1/2 MAP kinases: structure, function, and regulation

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21 June 2018

Sirtuins in cognitive ageing and Alzheimer's disease

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21 June 2018

Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding

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21 June 2018

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

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21 June 2018

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

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21 June 2018

The acetylation of tau inhibits its function and promotes pathological tau aggregation

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21 June 2018

Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?

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21 June 2018

Sirtuin-1 regulation of mammalian metabolism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039268

21 June 2018

Acetylation of tau inhibits its degradation and contributes to tauopathy

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21 June 2018

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039268

21 June 2018

Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice

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21 June 2018

Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease

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21 June 2018

High glucose induces transactivation of the alpha2-HS glycoprotein gene through the ERK1/2 signaling pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039268

21 June 2018

Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease

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21 June 2018

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

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21 June 2018

Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.

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21 June 2018

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

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21 June 2018

Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach

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21 June 2018

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

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21 June 2018

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

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21 June 2018

Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway

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21 June 2018

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

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21 June 2018

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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21 June 2018

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

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21 June 2018

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

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21 June 2018

Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease

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21 June 2018

Low-dose radiation hypersensitivity in human tumor cell lines: effects of cell-cell contact and nutritional deprivation

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21 June 2018

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

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21 June 2018

Phosphorylation of extracellular signal-regulated kinase after transient cerebral ischemia in hyperglycemic rats

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21 June 2018

Type 2 diabetes mellitus, cognitive impairment and dementia.

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21 June 2018

Binding properties of glutamate receptors in streptozotocin-induced diabetes in rats.

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21 June 2018

Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes

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21 June 2018

Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats.

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21 June 2018

Effect of naringenin on intracerebroventricular streptozotocin-induced cognitive deficits in rat: a behavioral analysis.

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21 January 2018

Experimental treatment for focal hyperglycemic ischemic brain injury in the rat.

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21 January 2018

Effects of streptozotocin-diabetes on the hippocampal NMDA receptor complex in rats.

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21 January 2018

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein.

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21 January 2018

The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways

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21 January 2018

Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin

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21 January 2018

Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats.

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Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex

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Diabetes mellitus as a modulator of functional impairment and decline in Alzheimer's disease. The Real.FR cohort

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Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents.

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Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses

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Expressions of Abeta1-40, Abeta1-42, tau202, tau396 and tau404 after intracerebroventricular injection of streptozotocin in rats

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Effects of hyperglycemic and normoglycemic cerebral ischemia on phosphorylation of c-jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK).

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Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease.

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Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease?

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Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type

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Identifiers

10.1007/S11357-013-9592-1

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Europe PubMed Central

28 July 2017

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Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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