Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding (Q33676732)

28 July 2017

Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding (English)

1 reference

28 July 2017

13

Magnar Bjørås

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Inger Sandlie

16

object named as

Inger Sandlie

1 reference

28 July 2017

1

Jan Terje Andersen

1 reference

28 July 2017

Bjørn Dalhus

2

1 reference

28 July 2017

Dorthe Viuff

3

1 reference

28 July 2017

Birgitte Thue Ravn

4

1 reference

28 July 2017

Kristin Støen Gunnarsen

5

1 reference

28 July 2017

Andrew Plumridge

6

1 reference

28 July 2017

Karen Bunting

7

1 reference

28 July 2017

Filipa Antunes

8

1 reference

28 July 2017

Rebecca Williamson

9

1 reference

28 July 2017

Steven Athwal

10

1 reference

28 July 2017

Elizabeth Allan

11

1 reference

28 July 2017

Leslie Evans

12

1 reference

28 July 2017

Søren Kjærulff

14

1 reference

28 July 2017

Darrell Sleep

15

1 reference

28 July 2017

Jason Cameron

17

1 reference

28 July 2017

language of work or name

English

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publication date

20 March 2014

1 reference

Journal of Biological Chemistry

28 July 2017

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28 July 2017

289

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28 July 2017

19

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28 July 2017

13492-13502

1 reference

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Albumin as a versatile platform for drug half-life extension

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Impact of albumin on drug delivery--new applications on the horizon.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Therapeutic antibodies for autoimmunity and inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Enhanced antibody half-life improves in vivo activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

FcRn binding properties of an abnormal truncated analbuminemic albumin variant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystallographic Analysis of Human Serum Albumin Complexed with 4Z,15E-Bilirubin-IXα

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Engineered human IgG antibodies with longer serum half-lives in primates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structural analysis of human serum albumin complexed with hemin and fatty acid

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structure of human serum albumin at 2.5 A resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Increasing the serum persistence of an IgG fragment by random mutagenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Crystal structure of the complex of rat neonatal Fc receptor with Fc

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

Quantitative analysis of protein far UV circular dichroism spectra by neural networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

A homozygote for a serum albumin variant of the fast type

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036356

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

Albumin binding to FcRn: distinct from the FcRn-IgG interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

The production, characterisation and enhanced pharmacokinetics of scFv-albumin fusions expressed in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.549832

Cloning and expression of the neonatal rat intestinal Fc receptor, a major histocompatibility complex class I antigen homolog

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24652290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24652290

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.549832

1 reference

28 July 2017

1 reference

28 July 2017

1 reference