Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients. (Q36250920)

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English	Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients.	scientific article

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scholarly article

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9 February 2020

Safety and pharmacokinetics of a novel recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in hemophilia B patients (English)

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9 February 2020

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coagulation factor IX

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pharmacokinetics

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based on heuristic

inferred from title

2

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9 February 2020

4

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9 February 2020

Valerie Chamouard

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Elena Santagostino

1

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9 February 2020

Robert Klamroth

3

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9 February 2020

Ingrid Pabinger-Fasching

5

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9 February 2020

Christine Voigt

6

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9 February 2020

Iris Jacobs

7

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9 February 2020

Massimo Morfini

8

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9 February 2020

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2 August 2012

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9 February 2020

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9 February 2020

120

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9 February 2020

2405-2411

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9 February 2020

12

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9 February 2020

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

1 October 2017

Implications of coagulation factor VIII and IX pharmacokinetics in the prophylactic treatment of haemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

1 October 2017

Half-life extension through albumin fusion technologies

1 reference

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1 October 2017

Venous access in haemophilic children: choice and management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

1 October 2017

The hemophilias--from royal genes to gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

1 October 2017

Potent antithrombin activity and delayed clearance from the circulation characterize recombinant hirudin genetically fused to albumin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

1 October 2017

Development of a long-acting insulin analog using albumin fusion technology

1 reference

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29 June 2018

A 6-year follow-up of dosing, coagulation factor levels and bleedings in relation to joint status in the prophylactic treatment of haemophilia

1 reference

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29 June 2018

Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B.

1 reference

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22 September 2018

Albinterferon Alfa-2b was not inferior to pegylated interferon-α in a randomized trial of patients with chronic hepatitis C virus genotype 1.

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22 September 2018

Genetic fusion to albumin improves the pharmacokinetic properties of factor IX.

1 reference

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22 September 2018

A survey of adherence to haemophilia therapy in six European countries: results and recommendations

1 reference

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22 September 2018

Comparative study of validity of clinical, X-ray and magnetic resonance imaging scores in evaluation and management of haemophilic arthropathy in children

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22 September 2018

Human recombinant factor IX: safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448255

22 September 2018

Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized

1 reference

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22 September 2018

Factor IX inhibitors and anaphylaxis in hemophilia B.

1 reference

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22 September 2018

Purified factor IX using monoclonal immunoaffinity technique: clinical trials in hemophilia B and comparison to prothrombin complex concentrates

1 reference

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22 September 2018

The design and analysis of half-life and recovery studies for factor VIII and factor IX. Factor VIII/Factor IX Scientific and Standardization Committee of the International Society for Thrombosis and Haemostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22859609

12 December 2020

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Identifiers

10.1182/BLOOD-2012-05-429688

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Europe PubMed Central

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9 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22859609%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

Europe PubMed Central

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9 February 2020

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