Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. (Q33641563)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19887067%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats (English)

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11 February 2020

1

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7

Barbara S Slusher

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11 February 2020

5

Ajit Thomas

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author name string

Jie Li

2

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11 February 2020

Eliot L Gardner

3

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11 February 2020

Charles R Ashby

4

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Krystyna Wozniak

6

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Zheng-Xiong Xi

8

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11 February 2020

language of work or name

English

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publication date

31 October 2009

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European Journal of Pharmacology

11 February 2020

published in

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11 February 2020

volume

627

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11 February 2020

issue

1-3

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page(s)

156-161

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Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism

11 February 2020

cites work

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Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR

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The preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268.

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Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain - relation to brain concentration

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NAAG peptidase as a therapeutic target: Potential for regulating the link between glucose metabolism and cognition

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The neurotransmitter N-acetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophrenia

21 June 2018

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The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693.

21 June 2018

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Cocaine-induced alterations in dopamine receptor signaling: implications for reinforcement and reinstatement

21 June 2018

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Glutamate systems in cocaine addiction

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GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism

21 June 2018

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Neurobiology of relapse to heroin and cocaine seeking: a review

21 June 2018

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Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens

21 June 2018

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Functions of N-acetyl-L-aspartate and N-acetyl-L-aspartylglutamate in the vertebrate brain: role in glial cell-specific signaling

21 June 2018

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N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system

21 June 2018

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Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes

21 June 2018

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21 June 2018

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Systemic and central amygdala injections of the mGluR(2/3) agonist LY379268 attenuate the expression of incubation of cocaine craving.

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine

30 October 2018

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Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-alpha-linked-acidic dipeptidase (NAALADASE).

30 October 2018

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Modulation of behavioral sensitization to cocaine by NAALADase inhibition.

30 October 2018

1 reference

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N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19887067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19887067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1' side chain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19887067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EJPHAR.2009.10.062

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19887067%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19887067%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference