The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693. (Q35827155)

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4 January 2020

title

The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693 (English)

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4 January 2020

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6

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author name string

J P van der Post

1

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S J de Visser

2

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M L de Kam

3

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M Woelfler

4

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D C Hilt

5

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E S Burak

7

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E Bortey

8

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B S Slusher

9

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T Limsakun

10

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A F Cohen

11

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J M A van Gerven

12

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language of work or name

English

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publication date

1 August 2005

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British Journal of Clinical Pharmacology

4 January 2020

published in

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volume

60

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issue

2

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page(s)

128-136

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Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers

4 January 2020

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Design of NAALADase inhibitors: a novel neuroprotective strategy

11 July 2018

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GCPII (NAALADase) inhibition prevents long-term diabetic neuropathy in type 1 diabetic BB/Wor rats

21 January 2018

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Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-alpha-linked-acidic dipeptidase (NAALADASE).

21 January 2018

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Central nervous system effects of subdissociative doses of (S)-ketamine are related to plasma and brain concentrations measured with positron emission tomography in healthy volunteers.

21 January 2018

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Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations

21 January 2018

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The effects of sub-anaesthetic doses of ketamine on memory, cognitive performance and subjective experience in healthy volunteers.

21 January 2018

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The sensitivity of pharmacodynamic tests for the central nervous system effects of drugs on the effects of sleep deprivation.

24 September 2018

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On the cerebro-protective effects of caroverine, a calcium-channel blocker and antiglutamatergic drug: double-blind, placebo-controlled, EEG mapping and psychometric studies under hypoxia.

24 September 2018

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Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury

24 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/16042665

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A simple mechanical ataxia-meter

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PubMed

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Design and pharmacological activity of phosphinic acid based NAALADase inhibitors

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PubMed

https://pubmed.ncbi.nlm.nih.gov/16042665

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Identifiers

DOI

10.1111/J.1365-2125.2005.02396.X

1 reference

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4 January 2020

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