Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors (Q33604681)

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English	Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors	scientific article

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scholarly article

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Europe PubMed Central

28 July 2017

Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors (English)

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Europe PubMed Central

28 July 2017

type 2 diabetes

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based on heuristic

inferred from title

Clare L Kirkpatrick

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Clare L Kirkpatrick

1

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Salvatore Piro

4

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Piero Marchetti

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Piero Marchetti

2

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object named as

Domenico Bosco

6

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author name string

Francesco Purrello

3

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Europe PubMed Central

28 July 2017

Marco Bugliani

5

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Europe PubMed Central

28 July 2017

Eelco J P de Koning

7

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Europe PubMed Central

28 July 2017

Marten A Engelse

8

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Europe PubMed Central

28 July 2017

Julie Kerr-Conte

9

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Europe PubMed Central

28 July 2017

François Pattou

10

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Europe PubMed Central

28 July 2017

Claes B Wollheim

11

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

10 June 2010

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Europe PubMed Central

28 July 2017

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Europe PubMed Central

28 July 2017

5

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Europe PubMed Central

28 July 2017

e11053

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Europe PubMed Central

28 July 2017

6

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Europe PubMed Central

28 July 2017

copyright license

Creative Commons Attribution 4.0 International

10 June 2010

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April 2022 Public Data File from Crossref

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Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion

1 reference

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21 June 2018

Single pancreatic beta cells co-express multiple islet hormone genes in mice

1 reference

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21 June 2018

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

1 reference

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21 June 2018

Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue

1 reference

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21 June 2018

Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker

1 reference

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21 June 2018

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

1 reference

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PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

1 reference

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miR-375 maintains normal pancreatic alpha- and beta-cell mass

1 reference

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TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

1 reference

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Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

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Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes

1 reference

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In Vitro Proliferation of Cells Derived From Adult Human -Cells Revealed By Cell-Lineage Tracing

1 reference

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Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection

1 reference

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21 June 2018

RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

1 reference

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21 June 2018

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

1 reference

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21 June 2018

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

1 reference

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21 June 2018

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

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21 June 2018

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

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21 June 2018

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

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21 June 2018

The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications

1 reference

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21 June 2018

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

1 reference

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21 June 2018

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

1 reference

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

1 reference

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

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21 June 2018

Maturity-onset diabetes of the young: clinical heterogeneity explained by genetic heterogeneity

1 reference

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Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

1 reference

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More powerful procedures for multiple significance testing

1 reference

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TCF7L2 expression in diabetic patients undergoing bariatric surgery.

1 reference

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The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients.

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Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

1 reference

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Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.

1 reference

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Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

1 reference

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Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

1 reference

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Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release

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An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures

1 reference

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Proliferation of sorted human and rat beta cells.

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Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

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Expression of ectonucleotide pyrophosphate phosphodiesterase and peroxisome proliferator activated receptor gamma in morbidly obese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20548773

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Degradation of amylin by insulin-degrading enzyme

1 reference

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Identification and purification of functional human beta-cells by a new specific zinc-fluorescent probe

1 reference

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Relationship between peroxisome proliferator-activated receptor gamma and retinoic acid receptor alpha gene expression in obese human adipose tissue

1 reference

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inferred from PubMed ID database lookup

Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20548773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0011053

1 reference

Europe PubMed Central

28 July 2017

2010PLoSO...511053K

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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