Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis (Q33552839)

28 July 2017

Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis (English)

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28 July 2017

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Calvin Yu-chian Chen

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author name string

Chien-yu Chen

1

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28 July 2017

Yea-huey Chang

2

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28 July 2017

Da-tian Bau

3

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28 July 2017

Hung-jin Huang

4

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28 July 2017

Fuu-jen Tsai

5

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28 July 2017

Chang-hai Tsai

6

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28 July 2017

13 July 2009

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Acta Pharmacologica Sinica

28 July 2017

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28 July 2017

30

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28 July 2017

8

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28 July 2017

1186-1194

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https://scigraph.springernature.com/pub.10.1038/aps.2009.100

28 July 2017

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High-throughput screening assay for new ligands at human melatonin receptors

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Discovery and characterization of a novel inhibitor of CDC25B, LGH00045.

21 June 2018

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Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors

21 June 2018

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Agonist-induced hump current production in heterologously-expressed human alpha4beta2-nicotinic acetylcholine receptors

21 June 2018

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A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile

21 June 2018

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Influence of an additional 2-amino substituent of the 1-aminoethyl pharmacophore group on the potency of rimantadine against influenza virus A.

21 June 2018

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3D pharmacophore based virtual screening of T-type calcium channel blockers

21 June 2018

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Recruitment pharmacophore for interleukin 5 receptor alpha antagonism

21 June 2018

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3',5'-cyclic nucleotide phosphodiesterase 11A: localization in human tissues

21 June 2018

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High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients

21 June 2018

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Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

21 June 2018

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Cyclic GMP phosphodiesterase-5: target of sildenafil

21 June 2018

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Phagocytic activity of leaves of Epimedium species on mouse reticuloendotherial system

21 June 2018

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Effects of Epimedium sagittatum Maxim. Polysaccharides on DNA synthesis of bone marrow cells of "yang deficiency" animal model caused by hydroxyurea

21 June 2018

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A novel perspective on designing the inhibitor of HER2 receptor

21 June 2018

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Novel selective inhibitors of hydroxyxanthone derivatives for human cyclooxygenase-2.

21 January 2018

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What is the effective component in suanzaoren decoction for curing insomnia? Discovery by virtual screening and molecular dynamic simulation

21 January 2018

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Discovery of a novel competitive inhibitor of PTP1B by high-throughput screening

21 January 2018

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A novel high-throughput format assay for HIV-1 integrase strand transfer reaction using magnetic beads

21 January 2018

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Deoxyschisandrin modulates synchronized Ca2+ oscillations and spontaneous synaptic transmission of cultured hippocampal neurons

21 January 2018

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Discovery of new potent human protein tyrosine phosphatase inhibitors via pharmacophore and QSAR analysis followed by in silico screening.

21 January 2018

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Pharmacophore identification of KSP inhibitors.

21 January 2018

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Synthesis and phosphodiesterase 5 inhibitory activity of novel pyrido[1,2-e]purin-4(3H)-one derivatives

21 January 2018

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Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11.

21 January 2018

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[Effect of epimedium sagittatum on soluble IL-2 receptor and IL-6 levels in patients undergoing hemodialysis]

31 October 2018

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12 December 2020

[Effect of Epimedium sagittatum on quality of life and cellular immunity in patients of hemodialysis maintenance]

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12 December 2020

Viagra, Levitra, and Cialis: what's the difference?

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12 December 2020

Farnesyltransferase pharmacophore model derived from diverse classes of inhibitors

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12 December 2020

Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore

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12 December 2020

[Effect of five species of Epimedium on growth of cartilage and proliferation of cartilage cell in vitro]

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12 December 2020

Molecular modeling studies of pyridopurinone derivatives--potential phosphodiesterase 5 inhibitors

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12 December 2020

Pharmacokinetics and tissue distribution of a novel PDE5 inhibitor, SK-3530, in rats

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12 December 2020

[Stimulatory action of Epimedium sagittatum (Sieb. et Zucc.) Maxim. on platelet aggregation in rats]

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12 December 2020

Discovering novel 3-nitroquinolines as a new class of anticancer agents

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https://api.crossref.org/works/10.1038%2FAPS.2009.100

7 January 2021

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Identifiers

DOI

10.1038/APS.2009.100

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Dimensions Publication ID

28 July 2017

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28 July 2017

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