Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation (Q33510472)

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English	Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation	scientific article

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scholarly article

1 reference

Europe PubMed Central

27 July 2017

Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation (English)

1 reference

Europe PubMed Central

27 July 2017

7

object named as

Edda Klipp

0 references

Matteo Barberis

object named as

Matteo Barberis

2

0 references

object named as

Marco Vanoni

6

0 references

author name string

Roberta Alfieri

1

1 reference

Europe PubMed Central

27 July 2017

Ferdinando Chiaradonna

3

1 reference

Europe PubMed Central

27 July 2017

Daniela Gaglio

4

1 reference

Europe PubMed Central

27 July 2017

Luciano Milanesi

5

1 reference

Europe PubMed Central

27 July 2017

Lilia Alberghina

8

1 reference

Europe PubMed Central

27 July 2017

publication date

15 October 2009

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Europe PubMed Central

27 July 2017

BMC Bioinformatics

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Europe PubMed Central

27 July 2017

10 Suppl 12

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Europe PubMed Central

27 July 2017

S16

1 reference

Europe PubMed Central

27 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2105-10-s12-s16

0 references

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

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Cyclin A-Cdk1 regulates the origin firing program in mammalian cells

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Balancing the decision of cell proliferation and cell fate

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28 July 2018

Prediction of key factor controlling G1/S phase in the mammalian cell cycle using system analysis.

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28 July 2018

Temporal organization of the cell cycle

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28 July 2018

Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events

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28 July 2018

A bistable Rb-E2F switch underlies the restriction point

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The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

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28 July 2018

A systems biology dynamical model of mammalian G1 cell cycle progression

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Rb loss causes cancer by driving mitosis mad.

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Analysis of a generic model of eukaryotic cell-cycle regulation

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A new description of cellular quiescence

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28 July 2018

The flexible evolutionary anchorage-dependent Pardee's restriction point of mammalian cells: how its deregulation may lead to cancer

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28 July 2018

Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation

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New insights into cyclins, CDKs, and cell cycle control

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G1 cell-cycle control and cancer

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Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

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28 July 2018

Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis

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28 July 2018

G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

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PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

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28 July 2018

Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes

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28 July 2018

Multisite phosphorylation and the countdown to S phase

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

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28 July 2018

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo

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28 July 2018

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication

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28 July 2018

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

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28 July 2018

Cell cycle control as a basis for cancer drug development (Review).

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28 July 2018

A long twentieth century of the cell cycle and beyond

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28 July 2018

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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28 July 2018

Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6

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28 July 2018

Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.

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28 July 2018

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

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The transcriptional program in the response of human fibroblasts to serum

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28 July 2018

KEGG: Kyoto Encyclopedia of Genes and Genomes

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28 July 2018

Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension

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28 July 2018

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

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28 July 2018

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

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28 July 2018

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

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28 July 2018

Initiation of DNA replication in eukaryotic cells

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28 July 2018

A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase

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28 July 2018

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

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Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

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28 July 2018

New functional activities for the p21 family of CDK inhibitors

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28 July 2018

Cancer cell cycles

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28 July 2018

Cell cycle control of DNA replication.

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28 July 2018

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

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28 July 2018

What is the restriction point?

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28 July 2018

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

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28 July 2018

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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28 July 2018

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

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28 July 2018

D-type cyclin-dependent kinase activity in mammalian cells

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28 July 2018

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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28 July 2018

p21-containing cyclin kinases exist in both active and inactive states

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28 July 2018

Inhibitors of mammalian G1 cyclin-dependent kinases

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28 July 2018

G1 phase heterogeneity in exponentially growing Swiss 3T3 mouse fibroblasts

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28 July 2018

Genetic control of the cell division cycle in yeast

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28 July 2018

A Restriction Point for Control of Normal Animal Cell Proliferation

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28 July 2018

G1 events and regulation of cell proliferation

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28 July 2018

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

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28 July 2018

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

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28 July 2018

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28 July 2018

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31 October 2018

Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation

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31 October 2018

p27Kip1 is inactivated in human colorectal cancer by cytoplasmic localization associated with activation of Akt/PKB.

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31 October 2018

Mathematical modeling and sensitivity analysis of G1/S phase in the cell cycle including the DNA-damage signal transduction pathway.

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31 October 2018

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31 October 2018

Cell size at S phase initiation: an emergent property of the G1/S network

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31 October 2018

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31 October 2018

p27Kip1 and cyclin dependent kinase 2 regulate passage through the restriction point

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31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

Bifurcation analysis of the regulatory modules of the mammalian G1/S transition

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31 October 2018

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31 October 2018

Regulation of the mammalian cell cycle: a model of the G1-to-S transition

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31 October 2018

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

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31 October 2018

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31 October 2018

The kinetic origins of the restriction point in the mammalian cell cycle.

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31 October 2018

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.

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31 October 2018

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

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31 October 2018

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

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31 October 2018

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase

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31 October 2018

Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor

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Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19828076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19828076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin-dependent kinase inhibitors in restriction point control, genomic stability, and tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19828076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using process diagrams for the graphical representation of biological networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/19828076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-dependent carbon metabolism and transformation in mouse fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19828076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2105-10-S12-S16

1 reference

Europe PubMed Central

27 July 2017

DBLP publication ID

journals/bmcbi/AlfieriBCGMVKA09

1 reference

DBLP Dataset 2021-01-02

28 January 2021

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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