Current data of targeted therapies for the treatment of triple-negative advanced breast cancer: empiricism or evidence-based? (Q33500786)

27 July 2017

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title

Current data of targeted therapies for the treatment of triple-negative advanced breast cancer: empiricism or evidence-based? (English)

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27 July 2017

4

Sandro Barni

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27 July 2017

1

Fausto Petrelli

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27 July 2017

2

Mary Cabiddu

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27 July 2017

3

Mara Ghilardi

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PubMed ID

19737114

27 July 2017

language of work or name

English

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publication date

1 October 2009

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Expert Opinion on Investigational Drugs

27 July 2017

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27 July 2017

18

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27 July 2017

10

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27 July 2017

1467-1477

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Molecular portraits of human breast tumours

27 July 2017

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How basal are triple-negative breast cancers?

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Triple-negative breast cancer: therapeutic options

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Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas

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Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases

21 January 2018

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Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer

21 January 2018

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BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells

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Platinum-based chemotherapy in triple-negative breast cancer.

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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A phase II study of Yondelis (trabectedin, ET-743) as a 24-h continuous intravenous infusion in pretreated advanced breast cancer

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Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer.

21 January 2018

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Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

21 January 2018

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The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer

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Imatinib mesylate (Gleevec) in advanced breast cancer-expressing C-Kit or PDGFR-beta: clinical activity and biological correlations

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KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations

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Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane

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Targeting Src in breast cancer

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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

21 January 2018

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Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

21 January 2018

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Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment

21 January 2018

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10.1517/13543780903222268

21 January 2018

Identifiers

DOI

1 reference

27 July 2017

1 reference

PubMed ID

19737114