Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells (Q33484728)

27 July 2017

Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells (English)

1 reference

27 July 2017

0 references

8

1 reference

27 July 2017

Jose C Garcia-Garcia

2

0 references

author name string

Dennis J Grab

1

1 reference

27 July 2017

Olga V Nikolskaia

3

1 reference

27 July 2017

Yuri V Kim

4

1 reference

27 July 2017

Amanda Brown

5

1 reference

27 July 2017

Carlos A Pardo

6

1 reference

27 July 2017

Yongqing Zhang

7

1 reference

27 July 2017

Brenda A Wilson

9

1 reference

27 July 2017

Ana Paula C de A Lima

10

1 reference

27 July 2017

Julio Scharfstein

11

1 reference

27 July 2017

J Stephen Dumler

12

1 reference

27 July 2017

language of work or name

English

0 references

publication date

21 July 2009

1 reference

PLoS Neglected Tropical Diseases

27 July 2017

1 reference

27 July 2017

3

1 reference

27 July 2017

7

1 reference

27 July 2017

e479

1 reference

Creative Commons CC0 License

27 July 2017

start time

21 July 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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The C3 domain of Pasteurella multocida toxin is the minimal domain responsible for activation of Gq-dependent calcium and mitogenic signaling

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21 June 2018

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21 June 2018

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21 June 2018

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Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease

21 June 2018

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Minocycline impedes African trypanosome invasion of the brain in a murine model

21 June 2018

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21 June 2018

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Diagnostic and neuropathogenesis issues in human African trypanosomiasis

21 June 2018

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Effects of leptin on memory processing

21 June 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 June 2018

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Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.

21 June 2018

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PAGE: parametric analysis of gene set enrichment

21 June 2018

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Borrelia burgdorferi, host-derived proteases, and the blood-brain barrier

21 June 2018

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The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.

21 June 2018

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Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression

21 June 2018

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Brain-derived neurotrophic factor activation of TrkB protects neurons from HIV-1/gp120-induced cell death

21 June 2018

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African trypanosome interactions with an in vitro model of the human blood-brain barrier

21 June 2018

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Pasteurella multocida toxin as a tool for studying Gq signal transduction

21 June 2018

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Cerebral vessel laminins and IFN-gamma define Trypanosoma brucei brucei penetration of the blood-brain barrier

21 June 2018

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A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei

21 June 2018

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Action of Pasteurella multocida toxin depends on the helical domain of Galphaq

21 June 2018

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Human African trypanosomiasis of the CNS: current issues and challenges

21 June 2018

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Differential Ca2+ signaling by thrombin and protease-activated receptor-1-activating peptide in human brain microvascular endothelial cells

21 June 2018

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In vitro induction of microglial and endothelial cell apoptosis by cerebrospinal fluids from patients with human African trypanosomiasis

21 June 2018

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21 June 2018

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Trypanosome hydrolases and the blood-brain barrier

21 June 2018

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The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity

21 June 2018

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Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion

21 June 2018

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Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes

21 June 2018

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Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity

21 June 2018

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Signaling pathways mediating anti-apoptotic action of neurotrophins

21 June 2018

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Differential modulation and subsequent blockade of mitogenic signaling and cell cycle progression by Pasteurella multocida toxin

21 June 2018

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Analysis by high density cDNA arrays of altered gene expression in human intestinal epithelial cells in response to infection with the invasive enteric bacteria Salmonella

21 June 2018

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beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

21 June 2018

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Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor.

21 June 2018

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Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.

21 June 2018

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Protease-activated receptor-2 (PAR-2) is present in the rat hippocampus and is associated with neurodegeneration.

21 June 2018

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Monitoring trypanosomiasis in space and time

21 June 2018

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21 June 2018

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21 January 2018

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21 June 2018

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21 June 2018

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Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function

21 June 2018

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21 June 2018

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Methylmercury-induced astrocytic swelling is associated with activation of the Na+/H+ antiporter, and is fully reversed by amiloride.

21 January 2018

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21 January 2018

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Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. involvement of Gq but not G11.

21 January 2018

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Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of G{alpha} proteins, G{alpha}q and G{alpha}12/13.

21 January 2018

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Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via G(q)alpha-coupled phospholipase C-beta1.

21 January 2018

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Cooperative expression of survival p-ERK and p-Akt signals in rat brain neurons after transient MCAO.

21 January 2018

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Seasonal effects of central leptin infusion on secretion of melatonin and prolactin and on SOCS-3 gene expression in ewes.

21 January 2018

1 reference

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African trypanosomiasis in the rat alters melatonin secretion and melatonin receptor binding in the suprachiasmatic nucleus

21 January 2018

1 reference

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Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes

21 January 2018

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Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

21 January 2018

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Deficiency of PAR-2 gene increases acute focal ischemic brain injury.

21 January 2018

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Meningoencephalitic African trypanosomiasis: Brain IL-10 and IL-6 are associated with protection from neuro-inflammatory pathology

21 January 2018

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PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathways

21 January 2018

1 reference

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Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis

21 January 2018

1 reference

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Assessment of rapid morphological changes associated with elevated cAMP levels in human orbital fibroblasts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19621073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of Gαq and phospholipase C‐β2 in human platelets activation by thrombin receptors PAR1 and PAR4: studies in human platelets deficient in Gαq and phospholipase C‐β2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19621073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

National Institute on Aging microarray facility--resources for gerontology research

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19621073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PNTD.0000479

1 reference

27 July 2017

1 reference

27 July 2017

1 reference