Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes (Q24291341)

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English	Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes	scientific article

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scholarly article

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Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes (English)

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F2R like trypsin receptor 1

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GOA release 2020-03-11

positive regulation of JNK cascade

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

T Kanke

1

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S R Macfarlane

2

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M J Seatter

3

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E Davenport

4

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A Paul

5

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R C McKenzie

6

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R Plevin

7

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language of work or name

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publication date

24 August 2001

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Journal of Biological Chemistry

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276

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34

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31657-66

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Molecular cloning of a potential proteinase activated receptor

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https://api.crossref.org/works/10.1074%2FJBC.M100377200

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Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

1 reference

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

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Protease-activated receptor 3 is a second thrombin receptor in humans

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Cloning and characterization of human protease-activated receptor 4

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Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues

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Proteinase-activated receptor-2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase

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Immunolocalization of protease-activated receptor-2 in skin: receptor activation stimulates interleukin-8 secretion by keratinocytes in vitro

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Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes

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21 January 2018

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

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The stress-activated protein kinase pathways

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Evidence of nuclear PKC/MAP-kinase cascade in guinea pig model of epidermal hyperproliferation

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Activation of p38 mitogen-activated protein kinase and caspases in UVB-induced apoptosis of human keratinocyte HaCaT cells

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Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

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Signal transduction through NF-kappa B.

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

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Identification and characterization of an IkappaB kinase

1 reference

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

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MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

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Platelet-activating factor induces NF-kappa B activation through a G protein-coupled pathway

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Evidence for proteinase-activated receptor-2 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells

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The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation.

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Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

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Regulation by hypoxia of endothelin-1-stimulated phospholipase D activity in sheep pulmonary artery cultured smooth muscle cells

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P2Y receptor-mediated inhibition of tumor necrosis factor alpha -stimulated stress-activated protein kinase activity in EAhy926 endothelial cells

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

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Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells

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Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.

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The alpha and eta isoforms of protein kinase C stimulate transcription of human involucrin gene

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Identification of PKC-isoform-specific biological actions using pharmacological approaches

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Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

1 reference

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

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Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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A protective role for protease-activated receptors in the airways

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Relaxant and contractile responses of porcine pulmonary arteries to thrombin and thrombin receptor activating peptides

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Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway

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The potential for isoenzyme-selective modulation of protein kinase C.

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IL-8 gene expression and production in human keratinocytes and their modulation by UVB

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10.1074/JBC.M100377200

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