Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM. (Q33380187)

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English	Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM. (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

object named as

Elena Lesma

1

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Anna Maria Di Giulio

object named as

Anna Maria Di Giulio

5

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author name string

Vera Grande

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Silvia Ancona

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Stephana Carelli

4

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Europe PubMed Central

PubMed publication ID

26 July 2017

Alfredo Gorio

6

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Europe PubMed Central

PubMed publication ID

26 July 2017

language of work or name

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publication date

29 October 2008

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Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

e3558

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

copyright license

Creative Commons Attribution 4.0 International

29 October 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis

1 reference

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mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.

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Survivin expression in tuberous sclerosis complex cells

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21 June 2018

Anti-EGFR therapies: clinical experience in colorectal, lung, and head and neck cancers

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21 June 2018

Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: epidermal growth factor is the required growth factor

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21 June 2018

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

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21 June 2018

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21 June 2018

Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration

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21 June 2018

Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors

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21 June 2018

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570214

21 June 2018

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570214

21 June 2018

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2570214

21 June 2018

The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms

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21 June 2018

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

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Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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21 June 2018

IGF-I stimulates intestinal muscle cell growth by activating distinct PI 3-kinase and MAP kinase pathways

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21 June 2018

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

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21 June 2018

Identification and characterization of the tuberous sclerosis gene on chromosome 16

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21 June 2018

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase

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21 June 2018

Refined localization of TSC1 by combined analysis of 9q34 and 16p13 data in 14 tuberous sclerosis families

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Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

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The genetic basis of tuberous sclerosis.

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Phosphorylation of tuberin as a novel mechanism for somatic inactivation of the tuberous sclerosis complex proteins in brain lesions

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Estrogen enhances whereas tamoxifen retards development of Tsc mouse liver hemangioma: a tumor related to renal angiomyolipoma and pulmonary lymphangioleiomyomatosis

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IGF-I stimulates human intestinal smooth muscle cell growth by regulation of G1phase cell cycle proteins

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21 January 2018

Effects of rapamycin in the Eker rat model of tuberous sclerosis complex

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Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models

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Proliferative synergy of ANG II and EGF in porcine aortic vascular smooth muscle cells

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12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0003558

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

2008PLoSO...3.3558L

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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