Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance (Q33320681)

25 July 2017

Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance (English)

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25 July 2017

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Corentin Cras-Méneur

6

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Bradley W. Doble

object named as

Bradley W Doble

4

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James R. Woodgett

object named as

James R Woodgett

11

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author name string

Katsuya Tanabe

1

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25 July 2017

Zhonghao Liu

2

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25 July 2017

Satish Patel

3

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25 July 2017

Lin Li

5

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25 July 2017

Sara C Martinez

7

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25 July 2017

Cris M Welling

8

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25 July 2017

Morris F White

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25 July 2017

Ernesto Bernal-Mizrachi

10

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25 July 2017

M Alan Permutt

12

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25 July 2017

language of work or name

English

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publication date

1 February 2008

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25 July 2017

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25 July 2017

6

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25 July 2017

2

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25 July 2017

e37

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Creative Commons Attribution 4.0 International

25 July 2017

start time

19 February 2008

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2245985/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion

21 June 2018

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Glycogen synthase kinase-3--an overview of an over-achieving protein kinase

21 June 2018

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Regulating insulin signaling and beta-cell function through IRS proteins

21 June 2018

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21 June 2018

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21 June 2018

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Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms

21 June 2018

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Long-term treatment with novel glycogen synthase kinase-3 inhibitor improves glucose homeostasis in ob/ob mice: molecular characterization in liver and muscle

21 June 2018

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New insights into the roles of insulin/IGF-I in the development and maintenance of beta-cell mass

21 June 2018

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Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

21 June 2018

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Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?

21 June 2018

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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells

21 June 2018

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Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium

21 June 2018

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21 June 2018

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The glamour and gloom of glycogen synthase kinase-3

21 June 2018

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Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

21 June 2018

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The interaction of glycogen synthase kinase-3 (GSK-3) with the cell cycle.

21 June 2018

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Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo

21 June 2018

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 June 2018

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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

21 June 2018

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Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

21 June 2018

1 reference

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 June 2018

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Pdx1 restores beta cell function in Irs2 knockout mice

21 June 2018

1 reference

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Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

21 June 2018

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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

21 June 2018

1 reference

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PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice

21 June 2018

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Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 June 2018

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 June 2018

1 reference

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Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes

21 June 2018

1 reference

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Relative hypoglycemia and hyperinsulinemia in mice with heterozygous lipoprotein lipase (LPL) deficiency. Islet LPL regulates insulin secretion

21 June 2018

1 reference

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Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice

21 June 2018

1 reference

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Disruption of IRS-2 causes type 2 diabetes in mice

21 June 2018

1 reference

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Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 June 2018

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 June 2018

1 reference

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Purification of CpG islands using a methylated DNA binding column

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2245985

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

31 October 2018

1 reference

12 December 2020

Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

12 December 2020

Multisite phosphorylation of glycogen synthase

1 reference

12 December 2020

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

12 December 2020

Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

1 reference

12 December 2020

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

1 reference

12 December 2020

Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.0060037

Identifiers

DOI

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25 July 2017

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25 July 2017

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