YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification (Q33292142)

25 July 2017

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification (English)

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25 July 2017

Christopher A. Maxwell

object named as

C Maxwell

10

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author name string

A H Davies

1

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25 July 2017

I Barrett

2

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25 July 2017

M R Pambid

3

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25 July 2017

K Hu

4

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25 July 2017

A L Stratford

5

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25 July 2017

S Freeman

6

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25 July 2017

I M Berquin

7

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25 July 2017

S Pelech

8

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25 July 2017

P Hieter

9

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25 July 2017

S E Dunn

11

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25 July 2017

language of work or name

English

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publication date

21 March 2011

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25 July 2017

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25 July 2017

30

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25 July 2017

34

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25 July 2017

3649-3660

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describes a project that uses

25 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3121916/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2011.82

0 references

cites work

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Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

21 June 2018

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Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

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Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice

21 June 2018

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Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis

21 June 2018

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Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy

21 June 2018

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Expression of LIM kinase 1 is associated with reversible G1/S phase arrest, chromosomal instability and prostate cancer

21 June 2018

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Lim kinases, regulators of actin dynamics

21 June 2018

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21 June 2018

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21 June 2018

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Formation of a nuclear complex containing the p53 tumor suppressor, YB-1, and the Werner syndrome gene product in cells treated with UV light

21 June 2018

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

21 June 2018

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Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

21 June 2018

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Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY.

21 June 2018

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21 June 2018

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Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells

21 June 2018

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Polo-like kinases (Plks) and cancer

21 June 2018

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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

21 June 2018

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LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1

21 June 2018

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YB-1 promotes strand separation in vitro of duplex DNA containing either mispaired bases or cisplatin modifications, exhibits endonucleolytic activities and binds several DNA repair proteins

21 June 2018

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The pleiotropic functions of the Y-box-binding protein, YB-1.

21 June 2018

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A role for LIM kinase in cancer invasion.

21 June 2018

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YB-1 as a Cell Cycle-regulated Transcription Factor Facilitating Cyclin A and Cyclin B1 Gene Expression

21 June 2018

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Centrosome aberrations: cause or consequence of cancer progression?

21 June 2018

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Mitosis-specific activation of LIM motif-containing protein kinase and roles of cofilin phosphorylation and dephosphorylation in mitosis

21 June 2018

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Role of BRCA gene dysfunction in breast and ovarian cancer predisposition

21 June 2018

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Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

21 June 2018

1 reference

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21 June 2018

The Hallmarks of Cancer

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Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen

21 June 2018

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Sequence-specific RNA recognition by the Xenopus Y-box proteins. An essential role for the cold shock domain.

21 June 2018

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 June 2018

1 reference

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Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements

21 June 2018

1 reference

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Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Y-box factor YB-1 predicts drug resistance and patient outcome in breast cancer independent of clinically relevant tumor biologic factors HER2, uPA and PAI-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.82

Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle.

21 January 2018

1 reference

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Enhanced coexpression of YB-1 and DNA topoisomerase II alpha genes in human colorectal carcinomas

31 October 2018

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.82

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Dimensions Publication ID

25 July 2017

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25 July 2017

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