Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase (Q33283188)

25 July 2017

Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase (English)

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25 July 2017

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Igor B Rogozin

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Aravind L Iyer

object named as

L Aravind

7

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Lakshminarayan M. Iyer

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object named as

Lakshminarayan M Iyer

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25 July 2017

Youri I Pavlov

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author name string

Lizhi Liang

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25 July 2017

Galina V Glazko

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25 July 2017

Victoria G Liston

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25 July 2017

Zeev Pancer

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25 July 2017

language of work or name

English

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publication date

29 April 2007

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25 July 2017

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25 July 2017

8

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25 July 2017

6

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25 July 2017

647-656

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https://scigraph.springernature.com/pub.10.1038/ni1463

25 July 2017

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cites work

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey

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Structural diversity of the hagfish variable lymphocyte receptors

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Antigen receptor genes and the evolution of a recombinase

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An ancient evolutionary origin of the Rag1/2 gene locus

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THE EVOLUTION OF ADAPTIVE IMMUNITY

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Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice.

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Chicken IgL variable region gene conversions display pseudogene donor preference and 5' to 3' polarity

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Fission yeast switches mating type by a replication-recombination coupled process

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Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination.

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A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

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Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment

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A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus

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B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities.

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Time scale for cyclostome evolution inferred with a phylogenetic diagnosis of hagfish and lamprey cDNA sequences

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New insights into alternative mechanisms of immune receptor diversification

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Identifiers

DOI

10.1038/NI1463

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Dimensions Publication ID

25 July 2017

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