Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. (Q33255121)

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English	Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.	scientific article

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29 December 2019

Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio (English)

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29 December 2019

apoptotic process

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Annick Mühlethaler-Mottet

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29 December 2019

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Marjorie Flahaut

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29 December 2019

Katia Balmas Bourloud

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29 December 2019

Katya Auderset

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29 December 2019

Roland Meier

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29 December 2019

Jean-Marc Joseph

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29 December 2019

Nicole Gross

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29 December 2019

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24 August 2006

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29 December 2019

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29 December 2019

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29 December 2019

214

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29 December 2019

https://scigraph.springernature.com/pub.10.1186/1471-2407-6-214

0 references

Persistent inhibition of FLIP(L) expression by lentiviral small hairpin RNA delivery restores death-receptor-induced apoptosis in neuroblastoma cells.

1 reference

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21 June 2018

Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines

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21 June 2018

Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.

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Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP.

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21 June 2018

Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).

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21 June 2018

Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells

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21 June 2018

Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP.

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21 June 2018

Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells

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21 June 2018

HDAC inhibitors for the treatment of cancer

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21 June 2018

Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling

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Sensitization of mesothelioma to TRAIL apoptosis by inhibition of histone deacetylase: role of Bcl-xL down-regulation

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Bcl-2-family proteins and the role of mitochondria in apoptosis

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The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.

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Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

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Neuroblastoma: biological insights into a clinical enigma

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21 June 2018

TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy

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21 June 2018

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21 June 2018

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

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21 June 2018

IAP proteins: blocking the road to death's door

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Death and anti-death: tumour resistance to apoptosis

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21 January 2018

Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia

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31 October 2018

Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

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31 October 2018

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

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21 January 2018

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

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21 January 2018

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis

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12 December 2020

based on heuristic

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The fundamental role of epigenetic events in cancer

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12 December 2020

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10.1186/1471-2407-6-214

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29 December 2019

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29 December 2019

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29 December 2019

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