Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells (Q33200320)

23 July 2017

Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells (English)

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23 July 2017

2

Glen C Balch

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23 July 2017

Suhail K Mithani

1

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23 July 2017

Sheng-Ru Shiou

3

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23 July 2017

Robert H Whitehead

4

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23 July 2017

Pran K Datta

5

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23 July 2017

R Daniel Beauchamp

6

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23 July 2017

language of work or name

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1 April 2004

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Journal of Surgical Research

23 July 2017

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23 July 2017

117

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23 July 2017

2

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23 July 2017

296-305

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TGF-beta and the Smad signal transduction pathway

23 July 2017

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Transcriptional control by the TGF-beta/Smad signaling system

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Mechanisms of cell cycle arrest in response to TGF-beta in progestin-dependent and -independent growth of mammary tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Smad3 mutant mice develop metastatic colorectal cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Critical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Type II TGF(beta) receptor expression in intestinal cell lines and in the intestinal tract

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Disruption of TGFbeta signaling pathways in human pancreatic cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Quantitative polymerase chain reaction using an external control mRNA for determination of gene expression in a heterogeneous cell population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

TGF beta signals through a heteromeric protein kinase receptor complex

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Regulation of cell proliferation by Smad proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-4804%2803%2900335-4

10.1016/S0022-4804(03)00335-4

7 January 2021

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DOI

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23 July 2017

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