A novel strategy to design binding molecules harnessing the modular nature of repeat proteins. (Q33186470)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

A novel strategy to design binding molecules harnessing the modular nature of repeat proteins (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Andreas Plückthun

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Patrik Forrer

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Michael T Stumpp

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

539

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

2-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

Novel frameworks as a source of high-affinity ligands

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Scaffolds for engineering novel binding sites in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Synthetic human antibodies and a strategy for protein engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

An artificial cell-cycle inhibitor isolated from a combinatorial library

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Genetic selection of peptide inhibitors of biological pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

'Anticalins': a new class of engineered ligand-binding proteins with antibody-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Green fluorescent protein as a scaffold for intracellular presentation of peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Directed evolution of high-affinity antibody mimics using mRNA display

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The fibronectin type III domain as a scaffold for novel binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Protein repeats: structures, functions, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The leucine-rich repeat as a protein recognition motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Topological characteristics of helical repeat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

When protein folding is simplified to protein coiling: the continuum of solenoid protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The ankyrin repeat: a diversity of interactions on a common structural framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The leucine-rich repeat: a versatile binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Consensus-derived structural determinants of the ankyrin repeat motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Recent improvements to the SMART domain-based sequence annotation resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Designed to be stable: crystal structure of a consensus ankyrin repeat protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

In vitro selection and evolution of functional proteins by using ribosome display

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

In vitro display technologies: novel developments and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

A structural basis of the interactions between leucine-rich repeats and protein ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Structure of an IkappaBalpha/NF-kappaB complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Crystal structure of a 12 ANK repeat stack from human ankyrinR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Two structures of cyclophilin 40: folding and fidelity in the TPR domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The tetratricopeptide repeat: a structural motif mediating protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Comparison of ARM and HEAT protein repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Correlation betweenin VitroStability andin VivoPerformance of Anti-GCN4 Intrabodies as Cytoplasmic Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Sequence statistics reliably predict stabilizing mutations in a protein domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

The consensus concept for thermostability engineering of proteins: further proof of concept

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

Structure of the TPR domain of p67phox in complex with Rac.GTP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900177-7

10.1016/S0014-5793(03)00177-7

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12650916%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference