Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen (Q31083153)

20 August 2017

Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen (English)

1 reference

20 August 2017

Jennifer R Mastroianni

series ordinal

1

1 reference

PMCID

2788835

20 August 2017

André J Ouellette

series ordinal

2

1 reference

PMCID

2788835

20 August 2017

language of work or name

English

0 references

publication date

17 August 2009

1 reference

Journal of Biological Chemistry

20 August 2017

1 reference

20 August 2017

284

1 reference

20 August 2017

41

1 reference

20 August 2017

27848-27856

1 reference

Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7).

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Mechanisms of alpha-defensin bactericidal action: comparative membrane disruption by Cryptdin-4 and its disulfide-null analogue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Multi-layered regulation of intestinal antimicrobial defense

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Salmonella induces prominent gene expression in the rat colon

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Matrix metalloproteinase-7 activation of mouse paneth cell pro-alpha-defensins: SER43 down arrow ILE44 proteolysis enables membrane-disruptive activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Molecular analysis of the bacterial microbiota in the human stomach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Paneth cell alpha-defensins: peptide mediators of innate immunity in the small intestine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Mammalian defensins in the antimicrobial immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Defensins: antimicrobial peptides of vertebrates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Proteus mirabilis ZapA metalloprotease degrades a broad spectrum of substrates, including antimicrobial peptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Expression and regulation of antimicrobial peptides in the gastrointestinal tract

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Defensins: antimicrobial peptides of innate immunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Antimicrobial characterization of human beta-defensin 3 derivatives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Barrett's esophagus: environmental influences in the progression of dysplasia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

The host-microbe interface within the gut

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Paneth cell trypsin is the processing enzyme for human defensin-5.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

The multifaceted Paneth cell

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

[beta]-defensins in lung host defense

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Defensins of vertebrate animals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Activation of Paneth cell alpha-defensins in mouse small intestine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Characterization of luminal paneth cell alpha-defensins in mouse small intestine. Attenuated antimicrobial activities of peptides with truncated amino termini

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Secretion of type II phospholipase A2 and cryptdin by rat small intestinal Paneth cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Bactericidal properties of murine intestinal phospholipase A2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Investigational approaches for studying the structures and biological functions of myeloid antimicrobial peptides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Mast cells and paneth cells in ulcerative colitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

The Paneth cells: an enigma.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Defensins. Natural peptide antibiotics of human neutrophils

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Mouse neutrophils lack defensins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Enteric defensins: antibiotic peptide components of intestinal host defense

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Cryptdins: antimicrobial defensins of the murine small intestine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

The Paneth cell: a source of intestinal lysozyme

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Cathelicidins: a family of endogenous antimicrobial peptides

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Antimicrobial peptides of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Defensins in granules of phagocytic and non-phagocytic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Symbiotic bacteria direct expression of an intestinal bactericidal lectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Cytokine-mediated regulation of antimicrobial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Quantitative interactions between cryptdin-4 amino terminal variants and membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

In vitro activation of the rhesus macaque myeloid alpha-defensin precursor proRMAD-4 by neutrophil serine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Purification and primary structure of murine cryptdin-1, a Paneth cell defensin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.050773

Cryptdins: endogenous antibiotic peptides of small intestinal Paneth cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Accumulation of abundant messenger ribonucleic acids during postnatal development of mouse small intestine.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788835

Degradation of human alpha- and beta-defensins by culture supernatants of Porphyromonas gingivalis strain 381

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19687006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19687006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

beta-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19687006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.050773

1 reference

20 August 2017

1 reference

20 August 2017

1 reference

PMCID

2788835