Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration (Q31079724)

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English	Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration	scientific article

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scholarly article

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Europe PubMed Central

28 June 2017

Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration (English)

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Europe PubMed Central

28 June 2017

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Igor Branchi

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Enrico Alleva

13

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Fiorella Malchiodi-albedi

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ORCID Public Data File 2021

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Zoë Bichler

2

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Europe PubMed Central

28 June 2017

Luisa Minghetti

3

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Europe PubMed Central

28 June 2017

Jean Maurice Delabar

4

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Europe PubMed Central

28 June 2017

Fiorella Malchiodi-Albedi

5

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Europe PubMed Central

28 June 2017

Marie-Claude Gonzalez

6

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Europe PubMed Central

28 June 2017

Zoubidda Chettouh

7

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Europe PubMed Central

28 June 2017

Alessia Nicolini

8

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Europe PubMed Central

28 June 2017

Caroline Chabert

9

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Europe PubMed Central

28 June 2017

Desmond J Smith

10

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Europe PubMed Central

28 June 2017

Edward M Rubin

11

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Europe PubMed Central

28 June 2017

Danièle Migliore-Samour

12

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28 June 2017

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1 May 2004

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28 June 2017

Journal of Neuropathology & Experimental Neurology

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28 June 2017

63

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Europe PubMed Central

28 June 2017

429-440

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Europe PubMed Central

28 June 2017

5

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Europe PubMed Central

28 June 2017

Too much of a good thing: mechanisms of gene action in Down syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

The DNA sequence of human chromosome 21

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Expression of the mnb (dyrk) protein in adult and embryonic mouse tissues.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Murine models for Down syndrome

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https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Studies of visual function and its decay in mice with hereditary retinal degeneration.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Behavioral and neuroanatomical characterization of FVB/N inbred mice.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Effects of phosphatidylserine on p38 mitogen activated protein kinase, cyclic AMP responding element binding protein and nuclear factor-kappaB activation in resting and activated microglial cells

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Transgenic and knock-out mouse pups: the growing need for behavioral analysis.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Behavioral phenotype of individuals with Down syndrome

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Enlarged cholinergic forebrain neurons and improved spatial learning in p75 knockout mice

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

New life in an old idea: the synaptic plasticity and memory hypothesis revisited

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Précis of O'Keefe & Nadel's The hippocampus as a cognitive map

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Behavioral tests of hippocampal function: simple paradigms complex problems

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Cell cycle and death control: long live Forkheads

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Forkhead transcription factors: key players in development and metabolism

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Cyclin ubiquitination: the destructive end of mitosis

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinal

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Cell cycle markers in the hippocampus in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Associations between congenital malformations and childhood cancer. A register-based case-control study

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Alzheimer's disease research enters a "new cycle": how significant?

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Cell cycle regulatory failure in neurones: causes and consequences.

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Alzheimer's disease as a loss of differentiation control in a subset of neurons that retain immature features in the adult brain

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Oxidative stress, cell cycle, and neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Disruption of CREB function in brain leads to neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F63.5.429

21 January 2018

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10.1093/JNEN/63.5.429

1 reference

Europe PubMed Central

28 June 2017

1 reference

Europe PubMed Central

28 June 2017

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