MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption (Q31014027)

12 September 2017

MEKK1 is essential for DT40 cell apoptosis in response to microtubule disruption (English)

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12 September 2017

R Kwan

1

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12 September 2017

J Burnside

series ordinal

2

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12 September 2017

T Kurosaki

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3

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12 September 2017

G Cheng

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4

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12 September 2017

language of work or name

English

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publication date

1 November 2001

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Molecular and Cellular Biology

12 September 2017

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12 September 2017

21

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12 September 2017

21

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12 September 2017

7183-7190

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describes a project that uses

12 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC99893/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells

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Signal transduction by the JNK group of MAP kinases

28 July 2018

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

28 July 2018

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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

28 July 2018

1 reference

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Checkpoints controlling mitosis

28 July 2018

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BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

28 July 2018

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The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review

28 July 2018

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Mitogen-activated protein kinase kinase kinase 1 activates androgen receptor-dependent transcription and apoptosis in prostate cancer

28 July 2018

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Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents

28 July 2018

1 reference

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Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

28 July 2018

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

28 July 2018

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Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

28 July 2018

1 reference

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Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

28 July 2018

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

28 July 2018

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Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53.

28 July 2018

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Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

28 July 2018

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Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

28 July 2018

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Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis

28 July 2018

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Microtubules and actin filaments: dynamic targets for cancer chemotherapy

28 July 2018

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Coupling cell division and cell death to microtubule dynamics

28 July 2018

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MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

28 July 2018

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

28 July 2018

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Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin

28 July 2018

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A rapid and simple method for the isolation of apoptotic DNA fragments.

28 July 2018

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Inactivation of Bcl-2 by phosphorylation

28 July 2018

1 reference

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Taxol induction of p21WAF1 and p53 requires c-raf-1.

28 July 2018

1 reference

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Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule dynamics

28 July 2018

1 reference

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Complexity in the spindle checkpoint

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99893

MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99893

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

25 November 2018

1 reference

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Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

25 November 2018

1 reference

12 December 2020

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

12 December 2020

Activation of MEKK by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Mapping pathways for mitogen-activated protein kinase activation

1 reference

12 December 2020

Taxol and estramustine-induced modulation of human prostate cancer cell apoptosis via alteration in bcl-xL and bak expression

1 reference

12 December 2020

10.1128/MCB.21.21.7183-7190.2001

Identifiers

DOI

1 reference

12 September 2017

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12 September 2017

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