An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase (Q30915736)

27 June 2017

An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase (English)

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27 June 2017

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3

Dunbrack RL Jr

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27 June 2017

Yi J

1

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27 June 2017

Arthur JW

series ordinal

2

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27 June 2017

Skalka AM

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4

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27 June 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

27 June 2017

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27 June 2017

275

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27 June 2017

49

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27 June 2017

38739-38748

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27 June 2017

The retroviral enzymes

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Retroviral integrase, putting the pieces together

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Structural determinants of metal-induced conformational changes in HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Divalent cations stimulate preferential recognition of a viral DNA end by HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Solution structure of the DNA binding domain of HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Zinc stimulates Mg2+-dependent 3'-processing activity of human immunodeficiency virus type 1 integrase in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Molecular mechanisms in retrovirus DNA integration

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

21 January 2018

The Protein Data Bank

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

A comparison of the crystallographic structures of two catalytic antibodies with esterase activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Backbone-dependent rotamer library for proteins. Application to side-chain prediction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Bayesian statistical analysis of protein side-chain rotamer preferences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

A brighter future for protein structure prediction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Mutational analysis of the integrase protein of human immunodeficiency virus type 2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

A metal-induced conformational change and activation of HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Inhibitors of human immunodeficiency virus integrase.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Monoclonal antibodies against HIV type 1 integrase: clues to molecular structure

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

Comparative modeling of CASP3 targets using PSI-BLAST and SCWRL

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

An essential interaction between distinct domains of HIV-1 integrase mediates assembly of the active multimer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005499200

21 January 2018

Identifiers

DOI

10.1074/JBC.M005499200

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27 June 2017

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