In vitro evolution of a T cell receptor with high affinity for peptide/MHC. (Q30861962)

17 August 2017

In vitro evolution of a T cell receptor with high affinity for peptide/MHC. (English)

1 reference

17 August 2017

P D Holler

1

1 reference

17 August 2017

P O Holman

2

1 reference

17 August 2017

E V Shusta

3

1 reference

17 August 2017

S O'Herrin

4

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17 August 2017

K D Wittrup

5

1 reference

17 August 2017

D M Kranz

6

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17 August 2017

language of work or name

English

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publication date

1 May 2000

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Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

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17 August 2017

97

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17 August 2017

10

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17 August 2017

5387-5392

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Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Selection of functional T cell receptor mutants from a yeast surface-display library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Biosynthetic polypeptide libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Isolation of anti-T cell receptor scFv mutants by yeast surface display

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

In thymic selection, peptide diversity gives and takes away

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Yeast surface display for screening combinatorial polypeptide libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Structural insights into the evolution of an antibody combining site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

MHC restriction in three dimensions: a view of T cell receptor/ligand interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Altered T cell receptor ligands trigger a subset of early T cell signals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Kinetic discrimination in T-cell activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

T-cell-receptor affinity and thymocyte positive selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

The specificity and orientation of a TCR to its peptide-MHC class II ligands

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Kinetic and affinity limits on antibodies produced during immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Somatic generation of immune diversity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

T-cell antigen receptor genes and T-cell recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Making antibody fragments using phage display libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25838

Ligand recognition by alpha beta T cell receptors

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.080078297

Junctional amino acids determine the maturation pathway of an antibody.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.080078297

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.080078297

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

21 January 2018

1 reference

12 December 2020

A residue in the center of peptide QL9 affects binding to both Ld and the T cell receptor

1 reference

12 December 2020

Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition

1 reference

12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

12 December 2020

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.080078297

1 reference

17 August 2017

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1 reference

17 August 2017

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