High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling (Q77769114)

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8 December 2019

title

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling (English)

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8 December 2019

author name string

G J Kersh

1

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8 December 2019

E N Kersh

2

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8 December 2019

D H Fremont

3

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8 December 2019

P M Allen

4

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8 December 2019

publication date

1 December 1998

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8 December 2019

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8 December 2019

volume

9

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8 December 2019

issue

6

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8 December 2019

page(s)

817-826

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T-cell-receptor affinity and thymocyte positive selection

8 December 2019

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T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity

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A Basis for Alloreactivity: MHC Helical Residues Broaden Peptide Recognition by the TCR

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

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Major histocompatibility complex class I allele‐specific peptide libraries: Identification of peptides that mimic an H‐Y T cell epitope

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CD4 Augments the Response of a T Cell to Agonist but Not to Antagonist Ligands

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The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation

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Binding of a soluble alpha beta T-cell receptor to superantigen/major histocompatibility complex ligands

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Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

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Essential flexibility in the T-cell recognition of antigen

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Fidelity of T Cell Activation Through Multistep T Cell Receptor ζ Phosphorylation

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T cell positive selection by a high density, low affinity ligand

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A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

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7 January 2021

The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands

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7 January 2021

Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition

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Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

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Kinetic proofreading in T-cell receptor signal transduction

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Kinetic discrimination in T-cell activation

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Identification of the components of the murine T cell antigen receptor complex

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Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

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7 January 2021

Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity

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7 January 2021

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

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Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

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The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes

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Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

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Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59

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7 January 2021

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Identifiers

DOI

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8 December 2019

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