AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion (Q30806095)

19 August 2017

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion (English)

1 reference

19 August 2017

1 reference

1 reference

1

Brian Cunniff

1 reference

19 August 2017

3

Nicholas H Heintz

1 reference

19 August 2017

Andrew J McKenzie

2

1 reference

PMCID

5007087

19 August 2017

Alan K Howe

series ordinal

4

1 reference

19 August 2017

6 July 2016

1 reference

Molecular Biology of the Cell

19 August 2017

1 reference

19 August 2017

27

1 reference

19 August 2017

17

1 reference

19 August 2017

2662-2674

1 reference

PMCID

5007087

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5007087/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

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AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs

21 June 2018

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Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction

21 June 2018

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Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates.

21 June 2018

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Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling

21 June 2018

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Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects

21 June 2018

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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

21 June 2018

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Compartmentalized AMPK signaling illuminated by genetically encoded molecular sensors and actuators

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Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect

21 June 2018

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Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate

21 June 2018

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Adaptive mitochondrial reprogramming and resistance to PI3K therapy.

21 June 2018

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Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5

21 June 2018

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Targeting mitochondria metabolism for cancer therapy

21 June 2018

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LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.

21 June 2018

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The Warburg effect: evolving interpretations of an established concept

21 June 2018

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The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.

21 June 2018

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ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

21 June 2018

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Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.

21 June 2018

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Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

21 June 2018

1 reference

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The regulation of mitochondrial dynamics

21 June 2018

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Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

21 June 2018

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A novel method for pulmonary research: assessment of bioenergetic function at the air-liquid interface

21 June 2018

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Actin dynamics, architecture, and mechanics in cell motility

21 June 2018

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How does cancer cell metabolism affect tumor migration and invasion?

21 June 2018

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Microtubules and actin crosstalk in cell migration and division

21 June 2018

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Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio

21 June 2018

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Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1

21 June 2018

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Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

21 June 2018

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Microtubules in cell migration

21 June 2018

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Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture.

21 June 2018

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The dark face of AMPK as an essential tumor promoter

21 June 2018

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Mitochondrial localization and the persistent migration of epithelial cancer cells

21 June 2018

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AMPK: a contextual oncogene or tumor suppressor?

21 June 2018

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LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence

21 June 2018

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Understanding metabolic regulation and its influence on cell physiology

21 June 2018

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Nutrient sensing, metabolism, and cell growth control

21 June 2018

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LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin

21 June 2018

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Mitochondrial network in glioma's invadopodia displays an activated state both in situ and in vitro: potential functional implications

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Physiological roles of mitochondrial reactive oxygen species

21 June 2018

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Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells

21 June 2018

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21 June 2018

Mitochondria and cancer

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LKB1 and AMP-activated protein kinase: regulators of cell polarity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

AMPK: a nutrient and energy sensor that maintains energy homeostasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Mitochondria: in sickness and in health

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Protein kinase A activity and anchoring are required for ovarian cancer cell migration and invasion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Activation of AMP-activated protein kinase is essential for lysophosphatidic acid-induced cell migration in ovarian cancer cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Regulation of axonal mitochondrial transport and its impact on synaptic transmission

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Novel invadopodia components revealed by differential proteomic analysis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Spatial aspects of intracellular information processing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Adiponectin inhibits lipopolysaccharide-induced adventitial fibroblast migration and transition to myofibroblasts via AdipoR1-AMPK-iNOS pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Positioning mitochondrial plasticity within cellular signaling cascades.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

LKB1 and AMPK in cell polarity and division

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

The selectivity of protein kinase inhibitors: a further update

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Three-dimensional microenvironments modulate fibroblast signaling responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

21 June 2018

Mitochondria on the move

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Energy-dependent regulation of cell structure by AMP-activated protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

The relationship between mitochondrial shape and function and the cytoskeleton.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Cell-signalling dynamics in time and space

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Crawling toward a unified model of cell mobility: spatial and temporal regulation of actin dynamics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Cell migration: integrating signals from front to back

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Purification and characterization of beta-actin-rich tumor cell pseudopodia: role of glycolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

A genetically encoded fluorescent reporter of ATP:ADP ratio

21 June 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E16-05-0286

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E16-05-0286

AMP-activated protein kinase mediates activity-dependent axon branching by recruiting mitochondria to axon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E16-05-0286

Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1091%2FMBC.E16-05-0286

Effect of 2-deoxy-D-glucose on various malignant cell lines in vitro.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007087

Organelle transport: mitochondria hitch a ride on dynamic microtubules

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27385336

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E16-05-0286

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

PMCID

5007087