Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121). (Q30758542)

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24 November 2019

title

Increased revascularization efficacy after administration of an adenovirus encoding VEGF(121) (English)

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24 November 2019

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5

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24 November 2019

author name string

Perrin LA

1

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24 November 2019

June JE

2

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24 November 2019

Rosebury W

3

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24 November 2019

Robertson A

4

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24 November 2019

Bruder JT

6

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24 November 2019

Kessler PD

7

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Keiser JA

8

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Gordon D

9

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24 November 2019

publication date

1 March 2004

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24 November 2019

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24 November 2019

volume

11

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issue

6

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page(s)

512-521

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Adenoviruses as gene-delivery vehicles

24 November 2019

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Transient cyclophosphamide treatment before intraportal readministration of an adenoviral vector can induce re-expression of the original gene construct in rat liver

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Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease

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Adenovirus-mediated gene transfer of VEGF(121) improves lower-extremity endothelial function and flow reserve

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Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease

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Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

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Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

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Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: preliminary clinical results

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High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

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Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

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Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF.

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Adenovirus-mediated VEGF(121) gene transfer stimulates angiogenesis in normoperfused skeletal muscle and preserves tissue perfusion after induction of ischemia

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Effective repeat administration with adenovirus vectors to the muscle

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VEGF gene delivery to myocardium: deleterious effects of unregulated expression

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Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice

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Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

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Identifiers

DOI

10.1038/SJ.GT.3302173

1 reference

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24 November 2019

1 reference